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AXSM logoAxsome Therapeutics, Inc. (AXSM) Earnings History

Annual and quarterly earnings data from 2013 to 2025

TTM Net Income
-$188M
Net Loss
TTM EPS
$-3.68
Diluted
YoY EPS Growth
+38.6%
Excellent
Net Margin
-28.7%
Profitability
Operating Margin-26.5%
Gross Margin92.6%
ROE-252.1%
ROA-29.1%
Highest Annual Net Income-$2M (2013)
Highest Quarterly EPS$-0.12 (Q4 2015)
Consecutive Profitable Years0 years
Q1 2026
Net Income-$65M
EPS$-1.26
QoQ Growth-126.0%Declining

Loading earnings history...

AXSM EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

AXSM Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202592.6%-26.5%-28.7%
202491.4%-72.7%-74.5%
202390.4%-85.7%-88.4%
202289.6%-359.3%-374.0%
2021---
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Axsome Therapeutics, Inc. (AXSM) Earnings Overview

As of May 8, 2026, Axsome Therapeutics, Inc. (AXSM) reported trailing twelve-month net income of -$188M, reflecting +38.6% year-over-year growth. The company earned $-3.68 per diluted share over the past four quarters, with a net profit margin of -28.7%.

Looking at the long-term picture, AXSM's historical earnings data spans multiple years. The company achieved its highest annual net income of -$2M in fiscal 2013.

Axsome Therapeutics, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including INVA ($504M net income, 63.8% margin), SUPN (-$29M net income, -5.4% margin), ACAD ($376M net income, 36.5% margin), AXSM has room to improve margins relative to the peer group. Compare AXSM vs INVA →

AXSM Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
AXSM logoAXSMCurrent
-$188M$-3.68-28.7%-252.1%+38.6%—
INVA logoINVA
$504M$5.9463.8%29.1%+816.7%
SUPN logoSUPN
-$29M$-0.50-5.4%-3.7%-151.5%
ACAD logoACAD
$376M$2.1836.5%39.9%+68.4%
INTR logoINTR
$1.3B$2.998.8%13.2%+40.1%
PRAX logoPRAX
-$327M$-11.31--45.8%-32.0%
Best in group
Lowest in group

AXSM Historical Earnings Data (2013–2025)

13 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$183M+36.2%-$169M$-3.68-28.7%-26.5%
2024-$287M-20.1%-$281M$-5.99-74.5%-72.7%
2023-$239M-27.8%-$232M$-5.27-88.4%-85.7%
2022-$187M-43.5%-$180M$-4.60-374.0%-359.3%
2021-$130M-26.7%-$125M$-3.47--
2020-$103M-50.6%-$99M$-2.83--
2019-$68M-120.7%-$67M$-2.05--
2018-$31M-7.0%-$33M$-1.15--
2017-$29M-6.4%-$27M$-1.27--
2016-$27M-122.8%-$28M$-1.42--

Full AXSM Stock Analysis

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Is AXSM Undervalued?

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Compare AXSM vs DBVT

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AXSM — Frequently Asked Questions

Quick answers to the most common questions about buying AXSM stock.

Is AXSM growing earnings?

AXSM EPS is $-3.68, with earnings growth accelerating to +38.6%. This exceeds the 5-year CAGR of N/A. TTM net income reached $-188M.

What are AXSM's profit margins?

Axsome Therapeutics, Inc. net margin is -28.7%, with operating margin at -26.5%. Below-average margins reflect competitive or cost pressures.

How consistent are AXSM's earnings?

AXSM earnings data spans 2013-2025. The accelerating earnings trend is +38.6% YoY. Historical data enables comparison across business cycles.

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AXSM Earnings Over Time (2014–2025)

Net income and EPS trends