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Iterum Therapeutics plc (ITRM) Total Return Calculator with Dividends Reinvested

Iterum Therapeutics plc

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The total return for Iterum Therapeutics plc (ITRM) stock is -96.89% over the past 12 months. So far it's down 90.16% this year. The 5-year total return is -99.80%, meaning $10,000 invested in ITRM stock 5 years ago would be worth $20 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in ITRM 1 year ago, it would be worth $336 today — you'd have lost $9,664.

With Dividends Reinvested$336-96.64%

Price Only (No DRIP)$336-96.64%

Period2025-05-07 → 2026-03-31

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in ITRM

1Y$311-$9,689 (-96.9%)-96.9% CAGR

3Y$279-$9,721 (-97.2%)-69.7% CAGR

5Y$20-$9,980 (-99.8%)-71.1% CAGR

10Y$2-$9,998 (-100.0%)-58.2% CAGR

15Y$2-$9,998 (-100.0%)-44.1% CAGR

20Y$2-$9,998 (-100.0%)-35.4% CAGR

30Y$2-$9,998 (-100.0%)-25.3% CAGR

Iterum Therapeutics plc did not pay dividends during this period. Total return = price return.

Loading ITRM total return...

As of 2026-05-06

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-90.16%	—	-90.16%	—	$984
1Y	-96.89%	-96.89%	-96.89%	—	$311
3Y	-97.21%	-69.66%	-97.21%	—	$279
5Y	-99.80%	-71.13%	-99.80%	—	$20
10Y	-99.98%	-58.25%	-99.98%	—	$2
15Y	-99.98%	-44.14%	-99.98%	—	$2
20Y	-99.98%	-35.38%	-99.98%	—	$2
30Y	-99.98%	-25.26%	-99.98%	—	$2

Risk & Highlights

Best Year+114.13%2023

Worst Year-86.79%2022

Max Drawdown-97.26%2025-07-11 → 2026-03-31

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-16.03%	-16.03%	—	+0.41%	-16.4pp
2025	-81.69%	-81.69%	—	+16.64%	-98.3pp
2024	-10.61%	-10.61%	—	+24.00%	-34.6pp
2023	+114.13%	+114.13%	—	+24.81%	+89.3pp
2022	-86.79%	-86.79%	—	-19.95%	-66.8pp

ITRM underperformed the S&P 500 by 128.21pp over the past year (-96.89% vs +31.32%).

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ITRM Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
ITRMIterum Therapeutics plc	$2M	—	-90.2%	-96.9%	—	-97.2%	-99.8%	-100.0%
PRAXPraxis Precision Medicines, Inc.	$7.6B	+9.0%	+18.0%	+860.9%	—	+2005.6%	-18.4%	-19.0%
NKTRNektar Therapeutics	$1.7B	+13.9%	+96.0%	+783.6%	—	+636.7%	-69.4%	-57.6%
SPROSpero Therapeutics, Inc.	$142M	-3.1%	+7.7%	+328.8%	—	+33.2%	-80.2%	-78.0%
VNDAVanda Pharmaceuticals Inc.	$440M	+6.7%	-9.8%	+70.3%	—	+7.4%	-57.5%	-13.6%
CMPXCompass Therapeutics, Inc.	$330M	-66.3%	-64.2%	+9.4%	—	-46.9%	-64.8%	-78.2%
MTNBMatinas BioPharma Holdings, Inc.	$4M	+23.6%	+9.7%	+7.0%	—	-97.9%	-98.3%	-97.6%
AGENAgenus Inc.	$137M	+3.2%	+20.4%	+31.0%	—	-87.8%	-93.1%	-93.5%
TARSTarsus Pharmaceuticals, Inc.	$2.8B	-7.7%	-19.8%	+39.4%	—	+315.4%	+126.9%	+214.7%
IQVIQVIA Holdings Inc.	$29.9B	+3.4%	-21.7%	+20.7%	—	-7.0%	-23.7%	+167.5%
CRLCharles River Laboratories International, Inc.	$9.0B	+8.0%	-10.2%	+57.5%	—	-4.3%	-46.0%	+124.7%

Compare:ITRM vs PRAX ITRM vs NKTR ITRM vs SPRO ITRM vs PRAX vs NKTR

About ITRM Dividend Returns

Iterum Therapeutics plc (ITRM) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of ITRM over the past year?

Iterum Therapeutics plc (ITRM) delivered a return of -96.89% over the past year. Since ITRM does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in ITRM be worth today?

A $10,000 investment in Iterum Therapeutics plc one year ago would be worth $311 today, representing a loss of $9,689.

Q3Does ITRM pay dividends?

Iterum Therapeutics plc (ITRM) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For ITRM, the total return equals the price-only return.

Q4Did ITRM beat the S&P 500?

No, Iterum Therapeutics plc (ITRM) underperformed the S&P 500 by 128.21 percentage points over the past year. ITRM delivered a total return of -96.89%, compared to the S&P 500's 31.32%. This means a passive S&P 500 index fund outperformed ITRM by 128.21pp during this period.

Q5What is ITRM's worst drawdown?

Iterum Therapeutics plc (ITRM) experienced a maximum drawdown of -97.26% over the past year, declining from its peak on 2025-07-11 to its trough on 2026-03-31. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is ITRM's long-term total return over 10, 20, or 30 years?

Here are Iterum Therapeutics plc (ITRM)'s long-term returns with dividends reinvested. Over 10 years, the total return is -100.0% (-58.2% CAGR) — $10,000 would have grown to $2. Over 20 years: -100.0% total return (-35.4% CAGR) — $10,000 → $2. Over 30 years: -100.0% total return (-25.3% CAGR) — $10,000 → $2. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was ITRM's best and worst year?

Iterum Therapeutics plc's best calendar year was 2023 with a total return of 114.1%. Its worst year was 2022 with a total return of -86.8%. This range shows the volatility investors should expect — the difference between the best and worst year is 200.9 percentage points.