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Xenon Pharmaceuticals Inc. (XENE) Total Return Calculator with Dividends Reinvested

Xenon Pharmaceuticals Inc.

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The total return for Xenon Pharmaceuticals Inc. (XENE) stock is +66.44% over the past 12 months. So far it's up 31.61% this year. The 5-year total return is +222.79%, meaning $10,000 invested in XENE stock 5 years ago would be worth $32,279 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in XENE 1 year ago, it would be worth $16,574 today — you'd have gained $6,574.

With Dividends Reinvested$16,574+65.74%

Price Only (No DRIP)$16,574+65.74%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in XENE

1Y$16,644+$6,644 (+66.4%)66.4% CAGR

3Y$13,778+$3,778 (+37.8%)11.3% CAGR

5Y$32,279+$22,279 (+222.8%)26.4% CAGR

10Y$87,526+$77,526 (+775.3%)24.2% CAGR

15Y$55,767+$45,767 (+457.7%)12.1% CAGR

20Y$55,767+$45,767 (+457.7%)9.0% CAGR

30Y$55,767+$45,767 (+457.7%)5.9% CAGR

Xenon Pharmaceuticals Inc. did not pay dividends during this period. Total return = price return.

Loading XENE total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	+31.61%	—	+31.61%	—	$13,161
1Y	+66.44%	66.44%	+66.44%	—	$16,644
3Y	+37.78%	11.27%	+37.78%	—	$13,778
5Y	+222.79%	26.41%	+222.79%	—	$32,279
10Y	+775.26%	24.23%	+775.26%	—	$87,526
15Y	+457.66%	12.14%	+457.67%	—	$55,767
20Y	+457.67%	8.97%	+457.67%	—	$55,767
30Y	+457.67%	5.90%	+457.67%	—	$55,767

Risk & Highlights

Best Year+119.10%2018

Worst Year-63.95%2017

Max Drawdown-25.57%2025-05-12 → 2025-05-28 · Recovered 2025-08-12

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-2.83%	-2.83%	—	+0.41%	-3.2pp
2025	+11.58%	+11.58%	—	+16.64%	-5.1pp
2024	-12.71%	-12.71%	—	+24.00%	-36.7pp
2023	+23.62%	+23.62%	—	+24.81%	-1.2pp
2022	+24.82%	+24.82%	—	-19.95%	+44.8pp

XENE outperformed the S&P 500 by 35.12pp over the past year (+66.44% vs +31.32%).

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XENE Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
XENEXenon Pharmaceuticals Inc.	$4.7B	+3.1%	+31.6%	+66.4%	—	+37.8%	+222.8%	+775.3%
PRAXPraxis Precision Medicines, Inc.	$7.6B	+9.0%	+18.0%	+860.9%	—	+2005.6%	-18.4%	-19.0%
ACADACADIA Pharmaceuticals Inc.	$3.7B	-3.8%	-17.9%	+47.7%	—	-0.3%	+2.5%	-22.3%
PTCTPTC Therapeutics, Inc.	$5.5B	-3.3%	-13.2%	+84.1%	—	+19.9%	+65.2%	+839.5%
ARVNArvinas, Inc.	$656M	-8.6%	-10.5%	+47.6%	—	-58.4%	-83.8%	-36.1%
OVIDOvid Therapeutics Inc.	$362M	+20.9%	+58.0%	+869.3%	—	-19.7%	-19.7%	-77.3%
LGNDLigand Pharmaceuticals Incorporated	$4.6B	+14.2%	+22.3%	+125.1%	—	+200.3%	+83.9%	+95.1%
NKTRNektar Therapeutics	$1.7B	+13.9%	+96.0%	+783.6%	—	+636.7%	-69.4%	-57.6%
ABBVAbbVie Inc.	$362.6B	-0.8%	-9.1%	+13.1%	+3.6pp	+52.0%	+102.8%	+306.7%
NVSNovartis AG	$283.1B	-2.9%	+10.5%	+38.5%	+4.3pp	+61.5%	+99.3%	+188.8%
JNJJohnson & Johnson	$541.3B	-6.8%	+9.0%	+48.8%	+3.4pp	+47.6%	+48.0%	+136.2%

Compare:XENE vs PRAX XENE vs ACAD XENE vs PTCT XENE vs PRAX vs ACAD

About XENE Dividend Returns

Xenon Pharmaceuticals Inc. (XENE) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of XENE over the past year?

Xenon Pharmaceuticals Inc. (XENE) delivered a return of 66.44% over the past year. Since XENE does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in XENE be worth today?

A $10,000 investment in Xenon Pharmaceuticals Inc. one year ago would be worth $16,644 today, representing a gain of $6,644.

Q3Does XENE pay dividends?

Xenon Pharmaceuticals Inc. (XENE) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For XENE, the total return equals the price-only return.

Q4Did XENE beat the S&P 500?

Yes, Xenon Pharmaceuticals Inc. (XENE) outperformed the S&P 500 by 35.12 percentage points over the past year. XENE delivered a total return of 66.44%, compared to the S&P 500's 31.32%. This 35.12pp alpha means investors in XENE earned more than a passive S&P 500 index fund.

Q5What is XENE's worst drawdown?

Xenon Pharmaceuticals Inc. (XENE) experienced a maximum drawdown of -25.57% over the past year, declining from its peak on 2025-05-12 to its trough on 2025-05-28. The stock recovered to its prior peak by 2025-08-12. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is XENE's long-term total return over 10, 20, or 30 years?

Here are Xenon Pharmaceuticals Inc. (XENE)'s long-term returns with dividends reinvested. Over 10 years, the total return is 775.3% (24.2% CAGR) — $10,000 would have grown to $87,526. Over 20 years: 457.7% total return (9.0% CAGR) — $10,000 → $55,767. Over 30 years: 457.7% total return (5.9% CAGR) — $10,000 → $55,767. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was XENE's best and worst year?

Xenon Pharmaceuticals Inc.'s best calendar year was 2018 with a total return of 119.1%. Its worst year was 2017 with a total return of -63.9%. This range shows the volatility investors should expect — the difference between the best and worst year is 183.0 percentage points.