Biotechnology
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5 / 10Stock Comparison
SCNI vs IBIO vs IMVT vs NVAX vs HALO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
SCNI vs IBIO vs IMVT vs NVAX vs HALO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $715K | $26M | $5.53B | $1.50B | $7.68B |
| Revenue (TTM) | $1M | $300K | $0.00 | $596M | $1.40B |
| Net Income (TTM) | $4M | $-25M | $-464M | $-88M | $317M |
| Gross Margin | -147.0% | -76.7% | — | 84.6% | 81.9% |
| Operating Margin | -7.4% | -76.6% | — | -11.2% | 58.4% |
| Forward P/E | — | — | — | 3.6x | 8.1x |
| Total Debt | $2M | $4M | $98K | $249M | $0.00 |
| Cash & Equiv. | $2M | $9M | $714M | $241M | $134M |
SCNI vs IBIO vs IMVT vs NVAX vs HALO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Scinai Immunotherap… (SCNI) | 100 | 0.0 | -100.0% |
| iBio, Inc. (IBIO) | 100 | 0.2 | -99.8% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| Novavax, Inc. (NVAX) | 100 | 20.0 | -80.0% |
| Halozyme Therapeuti… (HALO) | 100 | 268.6 | +168.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SCNI vs IBIO vs IMVT vs NVAX vs HALO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SCNI carries the broadest edge in this set and is the clearest fit for growth and quality.
- 99.2% revenue growth vs IMVT's -21.3%
- 356.7% margin vs IBIO's -82.5%
- 33.1% ROA vs IBIO's -57.9%, ROIC -60.1% vs -130.5%
Among these 5 stocks, IBIO doesn't own a clear edge in any measured category.
IMVT is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- +96.1% vs SCNI's -80.6%
NVAX ranks third and is worth considering specifically for growth exposure.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
- Lower P/E (3.6x vs 8.1x)
HALO is the clearest fit if your priority is income & stability and long-term compounding.
- beta 0.56
- 5.7% 10Y total return vs IMVT's 173.6%
- Beta 0.56, current ratio 4.66x
- Beta 0.56 vs NVAX's 2.11
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 99.2% revenue growth vs IMVT's -21.3% | |
| Value | Lower P/E (3.6x vs 8.1x) | |
| Quality / Margins | 356.7% margin vs IBIO's -82.5% | |
| Stability / Safety | Beta 0.56 vs NVAX's 2.11 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +96.1% vs SCNI's -80.6% | |
| Efficiency (ROA) | 33.1% ROA vs IBIO's -57.9%, ROIC -60.1% vs -130.5% |
SCNI vs IBIO vs IMVT vs NVAX vs HALO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
SCNI vs IBIO vs IMVT vs NVAX vs HALO — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
SCNI leads 1 • IBIO leads 0 • IMVT leads 0 • NVAX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
HALO and IMVT operate at a comparable scale, with $1.4B and $0 in trailing revenue. SCNI is the more profitable business, keeping 3.6% of every revenue dollar as net income compared to IBIO's -82.5%. On growth, HALO holds the edge at +51.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $1M | $300,000 | $0 | $596M | $1.4B |
| EBITDAEarnings before interest/tax | -$7M | -$22M | -$487M | -$47M | $945M |
| Net IncomeAfter-tax profit | $4M | -$25M | -$464M | -$88M | $317M |
| Free Cash FlowCash after capex | -$6M | -$19M | -$423M | -$96M | $645M |
| Gross MarginGross profit ÷ Revenue | -147.0% | -76.7% | — | +84.6% | +81.9% |
| Operating MarginEBIT ÷ Revenue | -7.4% | -76.6% | — | -11.2% | +58.4% |
| Net MarginNet income ÷ Revenue | +3.6% | -82.5% | — | -14.7% | +22.7% |
| FCF MarginFCF ÷ Revenue | -5.0% | -64.0% | — | -16.1% | +46.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +36.1% | -100.0% | — | -79.1% | +51.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +66.7% | +81.1% | +19.7% | -102.0% | -2.1% |
Valuation Metrics
SCNI leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
At 3.6x trailing earnings, NVAX trades at a 86% valuation discount to HALO's 25.5x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than HALO's 8.3x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $714,770 | $26M | $5.5B | $1.5B | $7.7B |
| Enterprise ValueMkt cap + debt − cash | $1M | $21M | $4.8B | $1.5B | $7.5B |
| Trailing P/EPrice ÷ TTM EPS | -0.15x | -0.94x | -9.97x | 3.63x | 25.46x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 8.09x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 1.11x |
| EV / EBITDAEnterprise value multiple | — | — | — | 2.56x | 8.34x |
| Price / SalesMarket cap ÷ Revenue | 0.55x | 64.74x | — | 1.34x | 5.50x |
| Price / BookPrice ÷ Book value/share | 0.16x | 1.16x | 5.83x | — | 165.47x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 11.91x |
Profitability & Efficiency
HALO leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-71 for IBIO. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SCNI's 0.28x. On the Piotroski fundamental quality scale (0–9), NVAX scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +45.8% | -71.3% | -47.1% | — | +6.5% |
| ROA (TTM)Return on assets | +33.1% | -57.9% | -44.1% | -7.4% | +12.5% |
| ROICReturn on invested capital | -60.1% | -130.5% | — | — | +73.4% |
| ROCEReturn on capital employed | -69.6% | -88.6% | -66.1% | +100.4% | +38.2% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 4 | 2 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.28x | 0.24x | 0.00x | — | — |
| Net DebtTotal debt minus cash | $606,000 | -$5M | -$714M | $8M | -$134M |
| Cash & Equiv.Liquid assets | $2M | $9M | $714M | $241M | $134M |
| Total DebtShort + long-term debt | $2M | $4M | $98,000 | $249M | $0 |
| Interest CoverageEBIT ÷ Interest expense | 3.35x | -128.89x | — | -5.10x | 46.08x |
Total Returns (Dividends Reinvested)
HALO leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $19 for SCNI. Over the past 12 months, IMVT leads with a +96.1% total return vs SCNI's -80.6%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs SCNI's -69.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -25.6% | -18.8% | +5.1% | +29.5% | -7.3% |
| 1-Year ReturnPast 12 months | -80.6% | +92.9% | +96.1% | +55.1% | -7.1% |
| 3-Year ReturnCumulative with dividends | -97.2% | -92.4% | +40.9% | +23.9% | +115.3% |
| 5-Year ReturnCumulative with dividends | -99.8% | -99.8% | +62.4% | -94.8% | +37.0% |
| 10-Year ReturnCumulative with dividends | -99.9% | -100.0% | +173.6% | -90.4% | +570.7% |
| CAGR (3Y)Annualised 3-year return | -69.6% | -57.7% | +12.1% | +7.4% | +29.1% |
Risk & Volatility
Evenly matched — IMVT and HALO each lead in 1 of 2 comparable metrics.
Risk & Volatility
HALO is the less volatile stock with a 0.56 beta — it tends to amplify market swings less than NVAX's 2.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs SCNI's 8.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.67x | 2.03x | 1.37x | 2.11x | 0.56x |
| 52-Week HighHighest price in past year | $6.18 | $3.82 | $30.09 | $11.97 | $82.22 |
| 52-Week LowLowest price in past year | $0.45 | $0.56 | $13.36 | $5.80 | $47.50 |
| % of 52W HighCurrent price vs 52-week peak | +8.8% | +42.9% | +90.5% | +77.1% | +79.3% |
| RSI (14)Momentum oscillator 0–100 | 45.2 | 44.3 | 60.2 | 64.4 | 52.4 |
| Avg Volume (50D)Average daily shares traded | 4.1M | 972K | 1.4M | 4.4M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: IMVT as "Buy", NVAX as "Buy", HALO as "Buy". Consensus price targets imply 95.0% upside for NVAX (target: $18) vs 20.2% for HALO (target: $78).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | — | $45.50 | $18.00 | $78.33 |
| # AnalystsCovering analysts | — | — | 23 | 23 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.3% | +4.5% |
HALO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). SCNI leads in 1 (Valuation Metrics). 1 tied.
SCNI vs IBIO vs IMVT vs NVAX vs HALO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is SCNI or IBIO or IMVT or NVAX or HALO a better buy right now?
For growth investors, Scinai Immunotherapeutics Ltd.
(SCNI) is the stronger pick with 99. 2% revenue growth year-over-year, versus 37. 6% for Halozyme Therapeutics, Inc. (HALO). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — SCNI or IBIO or IMVT or NVAX or HALO?
On trailing P/E, Novavax, Inc.
(NVAX) is the cheapest at 3. 6x versus Halozyme Therapeutics, Inc. at 25. 5x.
03Which is the better long-term investment — SCNI or IBIO or IMVT or NVAX or HALO?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -99. 8% for Scinai Immunotherapeutics Ltd. (SCNI). Over 10 years, the gap is even starker: HALO returned +570. 7% versus IBIO's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — SCNI or IBIO or IMVT or NVAX or HALO?
By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.
(HALO) is the lower-risk stock at 0. 56β versus Novavax, Inc. 's 2. 11β — meaning NVAX is approximately 277% more volatile than HALO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 28% for Scinai Immunotherapeutics Ltd. — giving it more financial flexibility in a downturn.
05Which is growing faster — SCNI or IBIO or IMVT or NVAX or HALO?
By revenue growth (latest reported year), Scinai Immunotherapeutics Ltd.
(SCNI) is pulling ahead at 99. 2% versus 37. 6% for Halozyme Therapeutics, Inc. (HALO). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -160. 0% for Scinai Immunotherapeutics Ltd.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — SCNI or IBIO or IMVT or NVAX or HALO?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus -45. 9% for iBio, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -46. 5% for IBIO. At the gross margin level — before operating expenses — IBIO leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is SCNI or IBIO or IMVT or NVAX or HALO more undervalued right now?
Analyst consensus price targets imply the most upside for NVAX: 95.
0% to $18. 00.
08Which pays a better dividend — SCNI or IBIO or IMVT or NVAX or HALO?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is SCNI or IBIO or IMVT or NVAX or HALO better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 56), +570. 7% 10Y return). iBio, Inc. (IBIO) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HALO: +570. 7%, IBIO: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between SCNI and IBIO and IMVT and NVAX and HALO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: SCNI is a small-cap high-growth stock; IBIO is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; NVAX is a small-cap high-growth stock; HALO is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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