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AMLXAmylyx Pharmaceuticals, Inc.
$33.88$3.8B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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AMLX logo

Amylyx Pharmaceuticals, Inc.

AMLX
NASDAQ · Biotechnology
$33.88
At close - Sep 8, 4:00 PM EDT - USD
Market Cap$3.77B
P/E-22.1x
52W High$41.14
Volume1.14M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Post-Withdrawal Cash Burn Threatens Amylyx Survival

Amylyx Pharmaceuticals has transitioned to a clinical-stage biotech following the voluntary withdrawal of Relyvrio, with zero revenue in 2026Q2 and a 78% sequential cash decline to $49.3M. The company's pipeline, including the PHOENIX trial failure, offers no ...

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

AMLX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

3/12 Beats

EPS beat 3 of last 12 quarters

02

Valuation risk

-167% Peers

P/E is 167% below peer median

03

Market leadership

RS 98 · Leader

High momentum (Outperforming 98% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystConfirmed earnings · Nov 5

Market performance

Price History →

Trailing total returns as of 9/9/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
AMLX+196.67%
S&P 500 (^GSPC)+12.12%
1-Year Return
AMLX+224.52%
S&P 500 (^GSPC)+18.05%
3-Year Return
AMLX+65.11%
S&P 500 (^GSPC)+71.82%
5-Year Return
AMLX+87.49%
S&P 500 (^GSPC)+68.75%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-22.1x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-22.1x
21.0x
0th· Low
EV/EBITDA
N/A
21.7x
N/A
Price/FCF
N/A
96.5x
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$145M+52.0% YoY
Free cash flow
-$123M+26.4% YoY
Operating margin
-
ROIC (TTM)-132.2%
Avg ROIC 5Y-
ROE (TTM)-61.6%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate3/12 (25%)
Revenue Beat Rate1/12 (20%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.39-8.1%
vs -$0.36
—
vs —
Q2 2026
May 7, 2026
-$0.37-8.8%
vs -$0.34
—
vs —
Q2 2026
Mar 3, 2026
-$0.30+3.2%
vs -$0.31
—
vs $52,000
Q4 2025
Nov 6, 2025
-$0.37+14.0%
vs -$0.43
—
vs $52,000
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
The Motley Fool·Sep 1, 2026
Is GLP-1 Stock Amylyx Still a Buy After Skyrocketing 247%?

Amylyx Pharmaceuticals raised $500 million to strengthen its balance sheet. A potential 2027 drug launch could provide the company's next catalyst.

Defense World·Aug 29, 2026
BlackRock Inc. Acquires New Stake in Amylyx Pharmaceuticals, Inc. $AMLX

BlackRock Inc. bought a new position in shares of Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) in the undefined quarter, according to its most recent 13F filing with the Securities and Exchange Commission. The fund bought 8,827,085 shares of the company's stock, valued at approximately $158,534,000. BlackRock Inc. owned approximately 7.94% of Amylyx Pharmaceuticals as

Defense World·Aug 29, 2026
BlackRock Inc. Acquires New Stake in Amylyx Pharmaceuticals, Inc. $AMLX

BlackRock Inc. bought a new position in shares of Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) in the undefined quarter, according to its most recent 13F filing with the Securities and Exchange Commission. The fund bought 8,827,085 shares of the company's stock, valued at approximately $158,534,000. BlackRock Inc. owned approximately 7.94% of Amylyx Pharmaceuticals as

Market Watch·Aug 27, 2026
20 stocks likely to lose money even if the bull market continues

Certain stocks are such poor bets that they are likely to lose ground even in bull markets.

Filtered for Amylyx Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark AMLX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Amylyx Pharmaceuticals, Inc. (AMLX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AMLX logoAMLXAmylyx Pharmaceuticals, Inc.Current
$33.88$3.77B-22.14-100%—-61.59%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$56.71$9.42B-23.8333.87%-64.64%-110.84%—
BIIB logoBIIBBiogen Inc.
$212.50$31.4B24.071.39%8.39%4.52%—
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.
$534.16$12.32B-41.57432.05%-25.32%-56.65%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$27.58$4.72B12.0411.87%33.42%32.39%—
PRTA logoPRTAProthena Corporation plc
$9.54$499.45M-2.11-92.84%-80.67%-14.98%—

Compare AMLX vs Peers

Amylyx Pharmaceuticals, Inc. (AMLX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IONS

Most directly comparable listed peer for AMLX.

Scale Benchmark

vs IQV

Larger-name benchmark to compare AMLX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IONS, BIIB, MDGL, ACAD

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

AMLX SEC Filings & Documents

Amylyx Pharmaceuticals, Inc. (AMLX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jun 4, 2026·SEC

Material company update

May 7, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 3, 2026·SEC

FY 2025

Mar 4, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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AMLX Frequently Asked Questions

Amylyx Pharmaceuticals, Inc. (AMLX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
How fast is Amylyx Pharmaceuticals, Inc. growing?

Amylyx Pharmaceuticals, Inc. (AMLX) saw revenue decline by 100.0% over the past year.

Is AMLX profitable?

Amylyx Pharmaceuticals, Inc. (AMLX) reported a net loss of $152.1M for fiscal year 2025.

Dividend & Returns
What is AMLX's return on equity?

Amylyx Pharmaceuticals, Inc. (AMLX) has a return on equity (ROE) of -61.6%. Negative ROE indicates the company is unprofitable.

What is Amylyx Pharmaceuticals, Inc.'s free cash flow?

Amylyx Pharmaceuticals, Inc. (AMLX) had negative free cash flow of $126.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in AMLX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →