Axsome Therapeutics, Inc. (AXSM) P/E Ratio History
Historical price-to-earnings valuation from 2026 to 2026
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AXSM Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 6, 2026, Axsome Therapeutics, Inc. (AXSM) trades at a price-to-earnings ratio of -60.6x, with a stock price of $223.06 and trailing twelve-month earnings per share of $-3.68.
Compared to the Healthcare sector median P/E of 22.2x, AXSM trades at a 373% discount to its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 171.0x.
Relative to the broader market, AXSM trades at a notable discount to the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our AXSM DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
AXSM P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $2B | 6.9Lowest | 0.67 | +817%Best | |
| $4B | 16.4 | - | +468% | |
| $2B | 18.1 | 0.15Best | +176% | |
| $6B | 25.3 | - | -34% | |
| $5B | 8.4 | - | +264% |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
Full AXSM Stock Analysis
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Start ComparisonAXSM — Frequently Asked Questions
Quick answers to the most common questions about buying AXSM stock.
Is AXSM stock overvalued or undervalued?
AXSM current P/E: -60.6x. 5-year average P/E: N/A. Percentile: N/A.
How does AXSM's valuation compare to peers?
Axsome Therapeutics, Inc. P/E of -60.6x compares to sector median of 22.2x. The discount suggests lower growth expectations or higher risk.
What is AXSM's PEG ratio?
AXSM PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 2026-2026.