Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in CRSP held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | ARK Investment Management LLC | 9.5M | $516.0M | -16.4% | 9.809% | 3.35% |
| 2 | BlackRock, Inc. | 8.3M | $455.4M | +8.7% | 8.656% | 0.01% |
| 3 | Orbis Allan Gray Ltd | 5.4M | $297.2M | -10.8% | 5.650% | 1.02% |
| 4 | Capital World Investors | 4.7M | $259.0M | +0.5% | 4.924% | 0.03% |
| 5 | STATE STREET CORP | 4.3M | $235.7M | +8.5% | 4.481% | 0.00% |
| 6 | GSK plc | 3.2M | $175.7M | 0.0% | 3.339% | 29.17% |
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 2.5M | $136.9M | +5.6% | 2.602% | 0.01% |
| 8 | SR ONE CAPITAL MANAGEMENT, LP | 2.0M | $111.2M | 0.0% | 2.114% | 10.70% |
| 9 | TWO SIGMA INVESTMENTS, LP | 2.0M | $108.5M | +34.1% | 2.062% | 0.08% |
| 10 | FMR LLC | 1.9M | $104.1M | -2.4% | 1.979% | 0.00% |
| 11 | Sumitomo Mitsui Trust Group, Inc. | 1.7M | $93.8M | -7.2% | 1.784% | 0.05% |
| 12 | Amova Asset Management Americas, Inc. | 1.7M | $93.8M | -7.2% | 1.783% | 1.21% |
| 13 | EcoR1 Capital, LLC | 1.4M | $75.8M | 0.0% | 1.440% | 3.68% |
| 14 | UBS Group AG | 1.3M | $72.0M | -25.1% | 1.369% | 0.01% |
| 15 | Capital International Investors | 1.3M | $69.2M | +6.9% | 1.315% | 0.01% |
| 16 | VANGUARD CAPITAL MANAGEMENT LLC | 1.2M | $64.5M | +3.4% | 1.225% | 0.00% |
| 17 | BANK OF AMERICA CORP /DE/ | 1.2M | $63.0M | +17.5% | 1.198% | 0.00% |
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.1M | $59.5M | -33.8% | 1.131% | 0.00% |
| 19 | NEA Management Company, LLC | 1.1M | $57.7M | 0.0% | 1.098% | 3.64% |
| 20 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.1M | $57.7M | +1.8% | 1.097% | 0.01% |
| 21 | CITADEL ADVISORS LLC | 1.0M | $55.2M | -24.9% | 1.049% | 0.00% |
| 22 | D. E. Shaw & Co., Inc. | 1.0M | $55.0M | +606.5% | 1.045% | 0.03% |
| 23 | MORGAN STANLEY | 880K | $48.0M | +31.7% | 0.912% | 0.00% |
| 24 | NORTHERN TRUST CORP | 863K | $47.1M | +7.6% | 0.895% | 0.01% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 649K | $35.4M | +18.6% | 0.673% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CRSP — a direct measure of their conviction.
Filings activity in CRSP during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new CRSP position in Q2 2026
Institutions that fully closed their CRSP position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 525 | +6.7% | 81.64% | 2.51 pp | $4.16B | +13% |
| Q1 2026 | 492 | +2.3% | 84.15% | 0.43 pp | $3.68B | 11% |
| Q4 2025 | 481 | +9.8% | 84.58% | +0.53 pp | $4.13B | 15% |
| Q3 2025 | 438 | +4.0% | 84.05% | +0.11 pp | $4.84B | +44% |
| Q2 2025 | 421 | +12% | 83.94% | +8.78 pp | $3.37B | +67% |
| Q1 2025 | 375 | 2.6% | 75.16% | +2.67 pp | $2.02B | 9.2% |
| Q4 2024 | 385 | 2.0% | 72.49% | +2.80 pp | $2.22B | 12% |
| Q3 2024 | 393 | — | 69.69% | — | $2.54B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CRSP stock.
Based on Q2 2026 13F filings, institutional ownership of CRISPR Therapeutics AG stands at 81.6%, held across 525 reporting institutions.
ARK Investment Management LLC is the largest reported institutional holder of CRSP, with approximately 9,460,939 shares worth $0.52B as of Q2 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of CRSP, including ARK Investment Management LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for CRSP is 58 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
69 institutions opened new positions in CRSP during Q2 2026, while 47 fully exited. 366 added to existing positions and 68 trimmed.
CRSP institutional ownership fell by 2.51 percentage points quarter-over-quarter, with a net change of +33 holders.
The top 10 institutions account for 57.7% of all reported 13F value in CRSP, and the top 25 account for 80.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
CRISPR Therapeutics AG (CRSP) Institutional Ownership