Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in CYRX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RAFFA WEALTH MANAGEMENT, LLC | 259K | $2.86B | — | 2.439% | 0.03% |
| 2 | BlackRock, Inc. | 4.2M | $66.2M | +6.0% | 39.683% | 0.00% |
| 3 | CADIAN CAPITAL MANAGEMENT, LP | 2.9M | $45.9M | -38.9% | 27.475% | 3.47% |
| 4 | MORGAN STANLEY | 2.3M | $35.7M | -50.2% | 21.418% | 0.00% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 2.2M | $33.8M | +1.6% | 20.244% | 0.00% |
| 6 | MILLENNIUM MANAGEMENT LLC | 1.7M | $27.1M | -41.9% | 16.225% | 0.01% |
| 7 | FRED ALGER MANAGEMENT, LLC | 1.5M | $24.3M | -9.1% | 14.537% | 0.08% |
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.5M | $24.1M | +86.6% | 14.448% | 0.00% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $20.6M | +5.1% | 12.346% | 0.00% |
| 10 | MAK CAPITAL ONE LLC | 1.3M | $20.1M | -10.3% | 12.016% | 2.81% |
| 11 | First Eagle Investment Management, LLC | 1.3M | $20.0M | +70.7% | 11.960% | 0.02% |
| 12 | Assenagon Asset Management S.A. | 1.2M | $18.1M | -23.0% | 10.840% | 0.01% |
| 13 | STATE STREET CORP | 1.0M | $16.4M | +6.4% | 9.848% | 0.00% |
| 14 | JANE STREET GROUP, LLC | 1.0M | $16.3M | +5.7% | 9.755% | 0.00% |
| 15 | DIMENSIONAL FUND ADVISORS LP | 1.0M | $15.7M | +8.3% | 9.408% | 0.00% |
| 16 | Nuveen, LLC | 923K | $14.5M | +817.3% | 8.682% | 0.00% |
| 17 | UBS Group AG | 868K | $13.6M | -6.9% | 8.168% | 0.00% |
| 18 | SILVERCREST ASSET MANAGEMENT GROUP LLC | 859K | $13.5M | -4.7% | 8.078% | 0.09% |
| 19 | Meros Investment Management, LP | 743K | $11.7M | +22.0% | 6.992% | 3.70% |
| 20 | NEEDHAM INVESTMENT MANAGEMENT LLC | 717K | $11.3M | +99.2% | 6.745% | 0.34% |
| 21 | BROWN CAPITAL MANAGEMENT LLC | 670K | $10.5M | -14.2% | 6.303% | 2.10% |
| 22 | DEUTSCHE BANK AG\ | 655K | $10.3M | -34.6% | 6.161% | 0.00% |
| 23 | Intrinsic Edge Capital Management LLC | 630K | $9.9M | 0.0% | 5.926% | 1.02% |
| 24 | BNP Paribas Asset Management Holding S.A. | 575K | $9.0M | -26.1% | 5.412% | 0.01% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 563K | $8.8M | +9.6% | 5.295% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CYRX — a direct measure of their conviction.
Filings activity in CYRX during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 187 | +13% | 199.99% | +104.19 pp | $3.58B | +832% |
| Q1 2026 | 166 | 2.4% | 95.80% | +2.37 pp | $385M | 9.2% |
| Q4 2025 | 170 | +7.6% | 93.43% | 44.14 pp | $424M | 35% |
| Q3 2025 | 158 | 1.3% | 137.57% | +44.10 pp | $650M | +97% |
| Q2 2025 | 160 | +6.7% | 93.47% | +2.10 pp | $330M | +26% |
| Q1 2025 | 150 | 5.7% | 91.37% | 3.71 pp | $262M | 25% |
| Q4 2024 | 159 | +7.4% | 95.08% | +0.22 pp | $350M | 2.3% |
| Q3 2024 | 148 | — | 94.86% | — | $358M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CYRX stock.
Based on Q2 2026 13F filings, institutional ownership of Cryoport, Inc. stands at 200.0%, held across 187 reporting institutions.
RAFFA WEALTH MANAGEMENT, LLC is the largest reported institutional holder of CYRX, with approximately 259,278 shares worth $2.86B as of Q2 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of CYRX, including MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, JANE STREET GROUP, LLC.
Our composite Smart Money Score for CYRX is 77 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
33 institutions opened new positions in CYRX during Q2 2026, while 15 fully exited. 137 added to existing positions and 9 trimmed.
CYRX institutional ownership rose by 104.19 percentage points quarter-over-quarter, with a net change of +21 holders.
The top 10 institutions account for 88.1% of all reported 13F value in CYRX, and the top 25 account for 93.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.