Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in GH held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 11.6M | $1.07B | +2.1% | 8.713% | 0.02% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 5.8M | $539.3M | β | 4.403% | 0.03% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 5.6M | $519.5M | β | 4.242% | 0.01% |
| 4 | Invesco Ltd. | 4.9M | $456.9M | -7.0% | 3.730% | 0.07% |
| 5 | GOLDMAN SACHS GROUP INC | 4.4M | $409.7M | +68.8% | 3.345% | 0.05% |
| 6 | TWO SIGMA INVESTMENTS, LP | 4.2M | $390.7M | +94.4% | 3.190% | 0.32% |
| 7 | FMR LLC | 4.1M | $380.2M | +71.8% | 3.104% | 0.02% |
| 8 | BAILLIE GIFFORD & CO | 3.9M | $356.5M | -21.1% | 2.910% | 0.36% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 3.5M | $324.2M | +9.2% | 2.646% | 0.02% |
| 10 | Capital International Investors | 3.5M | $321.6M | -1.3% | 2.625% | 0.08% |
| 11 | FRANKLIN RESOURCES INC | 3.4M | $318.5M | +2.6% | 2.600% | 0.08% |
| 12 | Deep Track Capital, LP | 3.3M | $308.4M | +19.2% | 2.518% | 6.36% |
| 13 | STATE STREET CORP | 2.9M | $266.5M | +3.2% | 2.175% | 0.01% |
| 14 | FULLER & THALER ASSET MANAGEMENT, INC. | 2.6M | $235.6M | +4.5% | 1.923% | 0.79% |
| 15 | EVENTIDE ASSET MANAGEMENT, LLC | 2.4M | $218.1M | -5.9% | 1.782% | 3.61% |
| 16 | ALLIANCEBERNSTEIN L.P. | 1.9M | $194.6M | +0.2% | 1.437% | 0.06% |
| 17 | FEDERATED HERMES, INC. | 1.9M | $174.4M | -7.1% | 1.423% | 0.28% |
| 18 | UBS ASSET MANAGEMENT AMERICAS INC | 1.6M | $150.0M | -15.3% | 1.224% | 0.03% |
| 19 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.5M | $140.8M | -28.9% | 1.149% | 1.03% |
| 20 | Alyeska Investment Group, L.P. | 1.5M | $137.6M | +10.9% | 1.123% | 0.39% |
| 21 | MORGAN STANLEY | 1.5M | $137.4M | +28.8% | 1.122% | 0.01% |
| 22 | RTW INVESTMENTS, LP | 1.5M | $136.8M | 0.0% | 1.117% | 1.36% |
| 23 | AMERIPRISE FINANCIAL INC | 1.5M | $135.0M | +91.6% | 1.102% | 0.03% |
| 24 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.5M | $134.1M | -0.4% | 1.095% | 0.02% |
| 25 | UBS Group AG | 1.4M | $130.7M | -17.3% | 1.067% | 0.02% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in GH β a direct measure of their conviction.
Filings activity in GH during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new GH position in Q1 2026
Institutions that fully closed their GH position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 474 | 2.9% | 66.10% | 6.64 pp | $11.54B | 9.1% |
| Q4 2025 | 488 | +28% | 72.74% | +30.87 pp | $12.70B | +74% |
| Q3 2025 | 380 | +6.1% | 41.87% | +6.43 pp | $7.31B | +18% |
| Q2 2025 | 358 | +7.5% | 35.44% | +6.07 pp | $6.19B | +21% |
| Q1 2025 | 333 | +14% | 29.37% | +8.80 pp | $5.13B | +43% |
| Q4 2024 | 292 | +12% | 20.57% | +4.83 pp | $3.59B | +31% |
| Q3 2024 | 261 | 7.4% | 15.74% | 2.09 pp | $2.75B | 12% |
| Q2 2024 | 282 | β | 17.83% | β | $3.11B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying GH stock.
Based on Q1 2026 13F filings, institutional ownership of Guardant Health, Inc. stands at 66.1%, held across 474 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of GH, with approximately 11,553,759 shares worth $1.07B as of Q1 2026.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of GH, including TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for GH is 34 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
77 institutions opened new positions in GH during Q1 2026, while 91 fully exited. 114 added to existing positions and 280 trimmed.
GH institutional ownership fell by 6.64 percentage points quarter-over-quarter, with a net change of -14 holders.
The top 10 institutions account for 41.3% of all reported 13F value in GH, and the top 25 account for 65.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.