Ionis Pharmaceuticals, Inc. (IONS) quarterly cash flow statement — complete operating, investing & financing history
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 | Q4'23 | Q3'23 | Q2'23 | Q1'23 | Q4'22 | Q3'22 | Q2'22 | Q1'22 | Q4'21 | Q3'21 | Q2'21 |
|---|
| Cash from Operations | -792.82M | -137.71M | -131.44M | 151.34M | -150.78M | -116.14M | -114.99M | -119.88M | -149.94M | 32.87M | -109.02M | -97.36M | -133.99M | -200.19M | -24.43M | -18.1M | -31.65M | 203.69M | -55.57M | -62.65M |
| Operating CF Margin % | -322.16% | -67.84% | -83.87% | 33.48% | -114.56% | -51.26% | -85.93% | -53.22% | -125.47% | 10.13% | -75.6% | -51.68% | -102.66% | -131.8% | -15.29% | -13.53% | -22.3% | 46.29% | -41.76% | -49.82% |
| Operating CF Growth % | -425.83% | -18.57% | -14.3% | 226.24% | -0.56% | -453.38% | -5.47% | -23.13% | -11.9% | 116.42% | -346.28% | -438.04% | -323.36% | -198.29% | 56.04% | 71.12% | 42.1% | 107.89% | -436.58% | -41.93% |
| Net Income | -92.53M | -229M | -128.61M | 123.55M | -146.94M | -104.35M | -140.48M | -66.27M | -142.8M | -9.26M | -147.41M | -85.29M | -124.32M | -52.43M | -46.99M | -105.14M | -65.17M | 224.61M | -82.47M | -80.88M |
| Depreciation & Amortization | 6.79M | 7.34M | 11.85M | 5.45M | 4.82B | 5.27M | 3.62M | 5.58M | 5.65M | 5.61M | 5.59M | 5.69M | 5.61M | 7.03M | 5.09M | 5.09M | 4.89M | 4.98M | 4.71M | 5.01M |
| Stock-Based Compensation | 43.27M | 0 | 31.15M | 29.69M | 29.72M | 36.15M | 31.98M | 30.73M | 31.34M | 26.34M | 25.96M | 26.56M | 26.95M | 25.69M | 23.84M | 24.5M | 26.24M | 22.26M | 30.54M | 30.02M |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.44M | -19.23M | 0 | 0 | 0 | 0 | 0 | 4.1M | 4.63M | 12.57M |
| Other Non-Cash Items | -20.23M | 60.09M | -115.49M | 21.13M | -4.81B | 8.18M | -149.66M | 4.1M | 1.39M | -72.93M | 4.07M | 6.47M | 12.78M | -149.61M | 2.93M | 5.94M | 6.14M | 2.93M | 1.72M | 1.94M |
| Working Capital Changes | -730.12M | 23.86M | 69.66M | -28.48M | -41.17M | -61.38M | 139.55M | -94.03M | -45.52M | 83.11M | -3.68M | -31.56M | -55M | -30.88M | -9.3M | 51.51M | -3.76M | -55.2M | -14.7M | -31.32M |
| Change in Receivables | -7.63M | -41.45M | -39.61M | -12.87M | 52.48M | -74.26M | 9.33M | -22.12M | 92.64M | 44.76M | -114.56M | -40.54M | 11.62M | -18.89M | 106K | 19.37M | 35.77M | -52.92M | 10.95M | -10.37M |
| Change in Inventory | 338K | 926K | 12.46M | -13.47M | 1.01M | -5.04M | 271K | 1.54M | -1.83M | 1.13M | -96K | -3.34M | -167K | -1.39M | -834K | 4.22M | 774K | -1.88M | 1.17M | -1.9M |
| Change in Payables | -3.1M | 13.76M | 20.31M | 5.66M | -25.97M | 35.2M | -2.15M | -3.19M | -13.87M | 0 | -17.98M | 15.81M | -10.29M | -4.51M | 8.28M | -5.55M | 2.88M | 4.74M | -7.92M | 6.75M |
| Cash from Investing | 536.82M | -419.5M | 91.34M | -120.07M | 170.46M | 68.21M | -340.8M | 62.45M | 76.11M | -26.71M | 68.71M | 69.52M | -325.64M | 212.15M | -183.93M | -3.3M | -287.55M | 95.11M | 121.97M | -101.03M |
| Capital Expenditures | -21.76M | -22.66M | -5.27M | -12.3M | -12.58M | -25.5M | -9.06M | -20.26M | -5.73M | 819K | -3.24M | -13.07M | -11.72M | -5.01M | -7.06M | -4.5M | -3.53M | -3.99M | -4.6M | -6.31M |
| CapEx % of Revenue | 8.84% | 11.16% | 3.36% | 2.72% | 9.56% | 11.25% | 6.77% | 8.99% | 4.8% | 0.25% | 2.25% | 6.94% | 8.98% | 3.3% | 4.42% | 3.36% | 2.49% | 0.91% | 3.46% | 5.02% |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.1M | 1.06M | 1.25M | 254.08M | 178.39M | -31K | 826M | 1.49M | 1.28M | 1.95M |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -1.49M | 0 | -1.66M | -1.96M | -651K | -2.55M | 12.75M | 0 | 0 | -770K | -1.1M | -1.06M | -1.25M | 0 | -178.39M | 31K | -826M | -1.49M | -1.28M | -1.95M |
| Cash from Financing | 57.26M | 591.18M | 81.22M | 1.25M | 2.2M | -44.12M | 496.05M | 2.56M | 23.57M | 40.72M | -32.27M | 143.54M | 492.09M | -51.02M | 1.83M | 1.22M | -7.33M | -62.49M | 1.46M | 314.54M |
| Debt Issued (Net) | -44K | 483.36M | -41K | -40K | -42K | -44.55M | -48K | -39K | -39K | -38K | -67.83M | 154.81M | -39K | -50.6M | -89K | 0 | 0 | 90.18M | 0 | 0 |
| Equity Issued (Net) | 57.3M | 107.82M | 81.26M | 1.29M | 2.24M | 429K | 496.1M | 2.6M | 23.61M | 40.76M | 3.73M | 2.39M | 2.56M | 343K | 2.57M | 1.61M | 1.85M | -15.61M | 1.92M | 1.88M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 31.84M | -13.66M | 489.57M | -765K | -645K | -399K | -9.17M | -137.06M | -464K | 312.66M |
| Net Change in Cash | -198.88M | 33.92M | 41.04M | 33.11M | 22.11M | -92.53M | 40.61M | -54.9M | -50.38M | 47.21M | -72.73M | 115.76M | 32.56M | -38.52M | -206.92M | -20.6M | -326.68M | 236.24M | 67.83M | 150.96M |
| Free Cash Flow | -814.58M | -159M | -134.74M | 137.07M | -163.35M | -141.64M | -124.05M | -140.14M | -155.67M | 33.68M | -112.26M | -110.44M | -145.72M | -205.2M | -31.49M | -22.6M | -35.18M | 199.7M | -60.17M | -68.96M |
| FCF Margin % | -331.01% | -78.33% | -85.98% | 30.32% | -124.12% | -62.51% | -92.7% | -62.22% | -130.27% | 10.38% | -77.85% | -58.61% | -111.64% | -135.1% | -19.71% | -16.89% | -24.79% | 45.39% | -45.21% | -54.84% |
| FCF Growth % | -398.67% | -12.26% | -8.62% | 197.81% | -4.94% | -520.48% | -10.5% | -26.9% | -6.83% | 116.42% | -256.51% | -388.7% | -314.19% | -202.76% | 47.67% | 67.23% | 38.99% | 119.2% | -157.93% | -24.57% |
| FCF per Share | -4.94 | -0.98 | -0.84 | 0.75 | -1.03 | -0.90 | -0.83 | -0.96 | -1.07 | 0.23 | -0.78 | -0.77 | -1.02 | -1.45 | -0.22 | -0.16 | -0.25 | 1.25 | -0.43 | -0.49 |
| FCF Conversion (FCF/Net Income) | 8.57x | 0.60x | 1.02x | 1.22x | 1.03x | 1.11x | 0.82x | 1.81x | 1.05x | -3.55x | 0.74x | 1.14x | 1.08x | 3.82x | 0.52x | 0.17x | 0.49x | 0.91x | 0.67x | 0.77x |
| Interest Paid | 0 | 0 | 185K | 5.12M | 0 | 5.16M | 145K | 5.47M | 95K | 0 | 423K | 440K | 89K | 694K | 0 | 0 | 594K | 1.25M | 661K | 2.27M |
| Taxes Paid | 0 | 0 | 371K | 0 | 0 | -2.07M | 80K | 1.98M | 13K | 0 | 204K | 217K | 293K | 5.01M | 0 | 0 | 2K | 35K | 3K | -2K |