Ionis Pharmaceuticals, Inc. (IONS) quarterly income statement — complete revenue, gross profit & net income history
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 | Q4'23 | Q3'23 | Q2'23 | Q1'23 | Q4'22 | Q3'22 | Q2'22 | Q1'22 | Q4'21 | Q3'21 | Q2'21 |
|---|
| Sales/Revenue | 246.09M | 203M | 156.72M | 452.05M | 131.61M | 226.58M | 133.81M | 225.25M | 119.5M | 324.5M | 144.21M | 188.41M | 130.52M | 151.89M | 159.77M | 133.79M | 141.92M | 440.01M | 133.09M | 125.75M |
| Revenue Growth % | 86.98% | -10.41% | 17.12% | 100.69% | 10.14% | -30.18% | -7.21% | 19.55% | -8.45% | 113.65% | -9.74% | 40.82% | -8.03% | -65.48% | 20.04% | 6.39% | 27.16% | 51.58% | -16.86% | -13.6% |
| Cost of Goods Sold | 2.98M | 8M | 2.34M | 4.15M | 1.5M | 3.83M | 1.07M | 4.16M | 2.15M | 3.06M | 2.19M | 2.54M | 1.34M | 3.69M | 1.51M | 4.75M | 4.17M | 2.23M | 3.08M | 2.96M |
| COGS % of Revenue | 1.21% | 3.94% | 1.49% | 0.92% | 1.14% | 1.69% | 0.8% | 1.85% | 1.8% | 0.94% | 1.52% | 1.35% | 1.03% | 2.43% | 0.95% | 3.55% | 2.94% | 0.51% | 2.31% | 2.35% |
| Gross Profit | 243.11M | 195M | 154.38M | 447.9M | 130.11M | 222.75M | 132.74M | 221.09M | 117.35M | 321.44M | 142.02M | 185.87M | 129.18M | 148.2M | 158.25M | 129.05M | 137.75M | 437.78M | 130.01M | 122.79M |
| Gross Margin % | 98.79% | 96.06% | 98.51% | 99.08% | 98.86% | 98.31% | 99.2% | 98.15% | 98.2% | 99.06% | 98.48% | 98.65% | 98.97% | 97.57% | 99.05% | 96.45% | 97.06% | 99.49% | 97.69% | 97.65% |
| Gross Profit Growth % | 86.85% | -12.46% | 16.3% | 102.59% | 10.88% | -30.7% | -6.53% | 18.94% | -9.16% | 116.89% | -10.26% | 44.04% | -6.22% | -66.15% | 21.72% | 5.09% | 26.34% | 52.55% | -17.18% | -13.85% |
| Operating Expenses | 360.53M | 410M | 314.56M | 308.08M | 276.97M | 333.57M | 281.4M | 287.18M | 266.86M | 327.57M | 285.28M | 276.07M | 243.33M | 356.22M | 217.41M | 214.56M | 195.25M | 217.18M | 215.86M | 195.76M |
| OpEx % of Revenue | 146.5% | 201.97% | 200.72% | 68.15% | 210.45% | 147.22% | 210.29% | 127.49% | 223.32% | 100.94% | 197.83% | 146.52% | 186.42% | 234.53% | 136.08% | 160.37% | 137.58% | 49.36% | 162.19% | 155.67% |
| Selling, General & Admin | 150.36M | 130M | 96.8M | 90.6M | 76.3M | 88.1M | 61.6M | 65.1M | 52.64M | 71M | 70M | 46.14M | 45.52M | 47.9M | 34.4M | 33.8M | 34.13M | 38.6M | 30.1M | 45.1M |
| SG&A % of Revenue | 61.1% | 64.04% | 61.77% | 20.04% | 57.97% | 38.88% | 46.03% | 28.9% | 44.05% | 21.88% | 48.54% | 24.49% | 34.87% | 31.54% | 21.53% | 25.26% | 24.05% | 8.77% | 22.62% | 35.86% |
| Research & Development | 210.17M | 280M | 217.75M | 217.46M | 200.76M | 245.49M | 219.76M | 222.06M | 214.22M | 256.56M | 215M | 230M | 198M | 308M | 182.99M | 180.76M | 161.13M | 179M | 184.77M | 139.31M |
| R&D % of Revenue | 85.4% | 137.93% | 138.95% | 48.11% | 152.54% | 108.35% | 164.23% | 98.59% | 179.26% | 79.06% | 149.09% | 122.07% | 151.7% | 202.78% | 114.54% | 135.1% | 113.53% | 40.68% | 138.83% | 110.78% |
| Other Operating Expenses | 0 | 0 | 9K | 22K | -87K | -21K | 38K | 13K | 0 | 11K | -49K | 0 | 0 | 50K | 16K | 2K | 0 | -1000K | 993K | 1000K |
| Operating Income | -117.42M | -215M | -160.18M | 139.82M | -146.86M | -110.82M | -148.66M | -66.09M | -149.51M | -6.12M | -143.26M | -90.19M | -114.15M | -208.02M | -59.15M | -85.51M | -57.5M | 220.6M | -85.85M | -72.97M |
| Operating Margin % | -47.72% | -105.91% | -102.21% | 30.93% | -111.59% | -48.91% | -111.09% | -29.34% | -125.12% | -1.89% | -99.35% | -47.87% | -87.45% | -136.95% | -37.03% | -63.92% | -40.52% | 50.14% | -64.5% | -58.03% |
| Operating Income Growth % | 20.04% | -94% | -7.75% | 311.55% | 1.77% | -1709.95% | -3.76% | 26.72% | -30.98% | 97.06% | -142.19% | -5.47% | -98.5% | -194.29% | 31.1% | -17.19% | 37.48% | 1073.29% | -134.96% | -40.99% |
| EBITDA | -117.42M | 4.6B | -155.68M | 145.27M | -141.46M | -105.56M | -143.16M | -60.51M | -143.86M | -511K | -137.67M | -84.51M | -108.54M | -200.99M | -54.06M | -80.43M | -52.61M | 225.59M | -81.14M | -67.95M |
| EBITDA Margin % | -47.72% | 2267.23% | -99.34% | 32.14% | -107.48% | -46.59% | -106.99% | -26.86% | -120.39% | -0.16% | -95.47% | -44.85% | -83.16% | -132.33% | -33.84% | -60.11% | -37.07% | 51.27% | -60.97% | -54.04% |
| EBITDA Growth % | 16.99% | 4460.23% | -8.74% | 340.07% | 1.67% | -20556.75% | -3.99% | 28.39% | -32.54% | 99.75% | -154.67% | -5.07% | -106.32% | -189.1% | 33.38% | -18.35% | 39.61% | 1346.28% | -152.9% | -42.39% |
| D&A (Non-Cash Add-back) | 0 | 4.82B | 4.5M | 5.45M | 5.4M | 5.27M | 5.49M | 5.58M | 5.65M | 5.61M | 5.59M | 5.69M | 5.61M | 7.03M | 5.09M | 5.09M | 4.89M | 4.98M | 4.71M | 5.01M |
| EBIT | -118M | -210M | -107.84M | 144.78M | -125.4M | -85.77M | -122.87M | -43.41M | -122.17M | 18.08M | -120.43M | -57.5M | -97.12M | -43.93M | -45.91M | -102.08M | -63.25M | 222.1M | -82.87M | -79.55M |
| Net Interest Income | -17M | -18M | 1.52M | 1.93M | 1.74M | 6.05M | 3.53M | 2.81M | 4.17M | 3.28M | 1.95M | 846K | 1.5M | 10.15M | 5.38M | 1.27M | -129K | -430K | -1.47M | 377K |
| Interest Income | 0 | 0 | 23.68M | 24.69M | 24.67M | 28.91M | 26.23M | 25.6M | 26.29M | 25.69M | 23.93M | 20.79M | 18.63M | 11.88M | 7.52M | 3.4M | 1.99M | 1.81M | 872K | 2.73M |
| Interest Expense | 17M | 18M | 22.16M | 22.76M | 22.93M | 22.86M | 22.69M | 22.79M | 22.11M | 22.41M | 21.98M | 19.95M | 17.12M | 1.73M | 2.14M | 2.13M | 2.12M | 2.24M | 2.34M | 2.36M |
| Other Income/Expense | 25.11M | -13M | 31.79M | -16.29M | 38K | 3.78M | 4.55M | -110K | 6.79M | 3.36M | 2.46M | 12.75M | 1.21M | 163.69M | 12.45M | -17.36M | -6.57M | 4.31M | 2.08M | -7.58M |
| Pretax Income | -92.31M | -228M | -128.39M | 123.53M | -146.82M | -107.04M | -144.1M | -66.2M | -142.73M | -2.77M | -140.81M | -77.45M | -112.94M | -44.33M | -46.71M | -102.88M | -64.07M | 224.92M | -83.77M | -80.55M |
| Pretax Margin % | -37.51% | -112.32% | -81.93% | 27.33% | -111.56% | -47.24% | -107.69% | -29.39% | -119.44% | -0.85% | -97.64% | -41.11% | -86.53% | -29.19% | -29.24% | -76.89% | -45.15% | 51.12% | -62.94% | -64.05% |
| Income Tax | 218K | 1M | 213K | -20K | 116K | -2.69M | -3.62M | 64K | 75K | 6.5M | 6.6M | 7.84M | 11.38M | 8.1M | 283K | 2.26M | 1.09M | 303K | -1.31M | 327K |
| Effective Tax Rate % | -0.24% | -0.44% | -0.17% | -0.02% | -0.08% | 2.51% | 2.51% | -0.1% | -0.05% | -234.77% | -4.69% | -10.13% | -10.08% | -18.27% | -0.61% | -2.2% | -1.71% | 0.13% | 1.56% | -0.41% |
| Net Income | -92.53M | -229M | -128.61M | 123.55M | -146.94M | -104.35M | -140.48M | -66.27M | -142.8M | -9.26M | -147.41M | -85.29M | -124.32M | -52.43M | -46.99M | -105.14M | -65.17M | 224.61M | -82.47M | -80.88M |
| Net Margin % | -37.6% | -112.81% | -82.06% | 27.33% | -111.64% | -46.05% | -104.98% | -29.42% | -119.5% | -2.85% | -102.22% | -45.27% | -95.25% | -34.52% | -29.41% | -78.58% | -45.92% | 51.05% | -61.96% | -64.31% |
| Net Income Growth % | 37.03% | -119.46% | 8.45% | 286.45% | -2.9% | -1026.51% | 4.7% | 22.31% | -14.86% | 82.33% | -213.69% | 18.88% | -90.78% | -123.34% | 43.02% | -30% | 27.49% | 166.01% | -237.05% | -215.47% |
| Net Income (Continuing) | -92.53M | -229M | -128.61M | 123.55M | -146.94M | -104.35M | -140.48M | -66.27M | -142.8M | -9.26M | -147.41M | -85.29M | -124.32M | -52.43M | -46.99M | -105.14M | -65.17M | 224.61M | -82.47M | -80.88M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.56 | -1.41 | -0.80 | 0.68 | -0.93 | -0.66 | -0.95 | -0.45 | -0.98 | -0.06 | -1.03 | -0.59 | -0.87 | -0.37 | -0.33 | -0.74 | -0.46 | 1.41 | -0.58 | -0.57 |
| EPS Growth % | 39.78% | -113.64% | 15.79% | 251.11% | 5.1% | -926.44% | 7.77% | 23.73% | -12.64% | 82.62% | -212.12% | 20.27% | -89.13% | -126.24% | 43.1% | -29.82% | 28.13% | 158.02% | -163.64% | -147.83% |
| EPS (Basic) | -0.56 | -1.41 | -0.80 | 0.78 | -0.93 | -0.66 | -0.95 | -0.45 | -0.98 | -0.06 | -1.03 | -0.59 | -0.87 | -0.37 | -0.33 | -0.74 | -0.46 | 1.59 | -0.58 | -0.57 |
| Diluted Shares Outstanding | 164.87M | 162M | 160.76M | 182.33M | 158.74M | 158M | 148.59M | 145.96M | 145.54M | 144M | 143.32M | 143.1M | 142.74M | 142M | 141.95M | 141.79M | 141.6M | 160M | 141.14M | 140.96M |
| Basic Shares Outstanding | 164.87M | 162M | 160.76M | 159.14M | 158.74M | 158M | 148.59M | 145.96M | 145.54M | 144M | 143.32M | 143.1M | 142.74M | 142M | 141.95M | 141.79M | 141.6M | 141M | 141.14M | 140.96M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |