MDGL trades 32.0% below Wall Street's consensus target of $677.00.
Last 12 months price action with 12-month analyst target path
The base valuation assumes MDGL achieves its forward estimates and maintains a stable P/E multiple of historical averagesx. This scenario reflects the blended consensus of 25 Wall Street analysts, balancing both positive catalysts and macroeconomic headwinds over the next 12 months.
As of September 24, 2026, Madrigal Pharmaceuticals, Inc. (MDGL) has a Wall Street consensus price target of $677.00, based on estimates from 25 covering analysts. With the stock currently trading at $513.02, this represents a potential upside of +32.0%. The company has a market capitalization of $11.83B.
Analyst price targets range from a low of $542.00 to a high of $962.00, representing a 62% spread in expectations. The median target of $649.00 aligns closely with the consensus average. The wide target spread reflects significant disagreement on fair value.
The current analyst consensus rating is Buy, with 22 analysts rating the stock as a Buy or Strong Buy,2 rating it Hold, and 1 rating it Sell or Strong Sell. This overwhelmingly bullish sentiment suggests analysts see significant catalysts for upside ahead.
From a valuation perspective, MDGL trades at a trailing P/E of -39.9x. Analysts expect EPS to grow +43.9% over the next year.
| Company | Market Cap | Price | Target | Upside Potential | Rating | Fwd P/E | Analysts |
|---|---|---|---|---|---|---|---|
 AKROAkero Therapeutics, Inc. | $4.5B | $54.65 | $48.40 | -11.4% | Buy | — | 14 |
 HIMSHims & Hers Health, Inc. | $6.3B | $28.39 | $32.17 | +13.3% | Hold | — | 20 |
 ELVNEnliven Therapeutics, Inc. | $3.3B | $46.09 | $76.00 | +64.9% | Buy | — | 9 |
 TERNTerns Pharmaceuticals, Inc. | $4.8B | $52.95 | $53.00 | +0.1% | Buy | — | 16 |
 GPCRStructure Therapeutics Inc. | $2.1B | $35.95 | $90.50 | +151.7% | Buy | — | 14 |
 NVCRNovocure Ltd | $1.9B | $16.25 | $26.00 | +60.0% | Buy | — | 15 |
 HALOHalozyme Therapeutics, Inc. | $13.3B | $112.44 | $103.00 | -8.4% | Buy | 13.4x | 27 |
 ARWRArrowhead Pharmaceuticals, Inc. | $9.4B | $66.96 | $104.43 | +56.0% | Buy | — | 22 |
 ALNYAlnylam Pharmaceuticals, Inc. | $32.9B | $246.51 | $347.33 | +40.9% | Buy | 36.9x | 52 |
 VKTXViking Therapeutics, Inc. | $4.9B | $41.65 | $91.75 | +120.3% | Buy | — | 24 |
Quick answers to the most common questions about buying MDGL stock.
The consensus Wall Street price target for MDGL is $677, representing 32.0% upside from the current price of $513.02. With 25 analysts covering the stock, this strong upside suggests significant value not yet reflected in today's share price.
MDGL has a consensus rating of "Buy" based on 25 Wall Street analysts. The rating breakdown is predominantly bullish, with 22 Buy/Strong Buy ratings. The consensus 12-month price target of $677 implies 32.0% upside from current levels.
MDGL's current price is $513.02 with a consensus target of $677 (32.0% implied move). Analyst estimates suggest the stock is undervalued at current levels.
The most bullish Wall Street analyst has a price target of $962 for MDGL, while the most conservative target is $542. The consensus of $677 represents the median expectation. These targets typically reflect 12-month expectations.
MDGL is heavily covered by Wall Street, with 25 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 22 have Buy ratings, 2 recommend Hold, and 1 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
The 12-month MDGL stock forecast based on 25 Wall Street analysts shows a consensus price target of $677, with estimates ranging from $542 (bear case) to $962 (bull case). The median consensus rating is "Buy".
Wall Street analysts are very optimistic on MDGL, with a "Buy" consensus rating and $677 price target (32.0% upside). 22 of 25 analysts rate it Buy or Strong Buy. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
MDGL analyst price targets range from $542 to $962, a 62% wide spread indicating significant analyst disagreement. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $677 consensus represents the middle ground.
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