Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in QURE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Avoro Capital Advisors LLC | 6.0M | $97.4M | -3.1% | 9.531% | 1.00% |
| 2 | abrdn plc | 5.3M | $86.8M | +44.3% | 8.486% | 0.14% |
| 3 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3.6M | $59.6M | -8.2% | 5.828% | 0.01% |
| 4 | Nantahala Capital Management, LLC | 2.8M | $46.4M | +305.7% | 4.537% | 2.39% |
| 5 | CITIGROUP INC | 2.8M | $46.0M | +1048.6% | 4.496% | 0.02% |
| 6 | TWO SIGMA INVESTMENTS, LP | 2.7M | $43.8M | +84.4% | 4.279% | 0.04% |
| 7 | RTW INVESTMENTS, LP | 2.6M | $42.3M | -30.3% | 4.136% | 0.42% |
| 8 | Caption Management, LLC | 2.5M | $41.3M | β | 4.038% | 0.39% |
| 9 | STATE STREET CORP | 2.3M | $37.0M | -30.0% | 3.615% | 0.00% |
| 10 | ORBIMED ADVISORS LLC | 2.1M | $34.9M | +189.7% | 3.416% | 0.74% |
| 11 | CITADEL ADVISORS LLC | 1.8M | $29.9M | +3.8% | 2.928% | 0.01% |
| 12 | 683 Capital Management, LLC | 1.8M | $28.7M | +54.5% | 2.804% | 2.22% |
| 13 | FMR LLC | 1.7M | $28.5M | -72.1% | 2.789% | 0.00% |
| 14 | BlackRock, Inc. | 1.7M | $28.3M | -12.2% | 2.772% | 0.00% |
| 15 | MPM Oncology Impact Management LP | 1.4M | $22.4M | -0.9% | 2.190% | 1.73% |
| 16 | Two Seas Capital LP | 1.3M | $21.3M | β | 2.079% | 0.88% |
| 17 | GOLDMAN SACHS GROUP INC | 1.3M | $20.7M | +8.2% | 2.020% | 0.00% |
| 18 | JENNISON ASSOCIATES LLC | 1.2M | $20.2M | -10.0% | 1.973% | 0.01% |
| 19 | Siren, L.L.C. | 1.0M | $16.4M | β | 1.599% | 0.45% |
| 20 | BALYASNY ASSET MANAGEMENT LLC | 964K | $15.8M | +610.9% | 1.542% | 0.05% |
| 21 | Integral Health Asset Management, LLC | 900K | $14.7M | 0.0% | 1.439% | 0.91% |
| 22 | Fiera Capital Corp | 817K | $13.4M | +6.3% | 1.306% | 0.05% |
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 805K | $13.2M | +3.7% | 1.287% | 0.00% |
| 24 | MILLENNIUM MANAGEMENT LLC | 793K | $13.0M | β | 1.268% | 0.01% |
| 25 | MAVERICK CAPITAL LTD | 698K | $11.4M | +5.4% | 1.116% | 0.13% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in QURE β a direct measure of their conviction.
Filings activity in QURE during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new QURE position in Q1 2026
Institutions that fully closed their QURE position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 199 | 7.4% | 64.04% | 28.40 pp | $1.10B | 31% |
| Q4 2025 | 215 | +1.9% | 92.44% | 100.80 pp | $1.59B | 52% |
| Q3 2025 | 211 | +51% | 193.24% | +140.96 pp | $3.33B | +270% |
| Q2 2025 | 140 | +5.3% | 52.28% | +21.93 pp | $901M | +72% |
| Q1 2025 | 133 | 0.7% | 30.35% | 13.25 pp | $523M | 30% |
| Q4 2024 | 134 | +4.7% | 43.60% | +32.30 pp | $752M | +286% |
| Q3 2024 | 128 | +11% | 11.30% | +3.27 pp | $195M | +41% |
| Q2 2024 | 115 | β | 8.03% | β | $138M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying QURE stock.
Based on Q1 2026 13F filings, institutional ownership of uniQure N.V. stands at 64.0%, held across 199 reporting institutions.
Avoro Capital Advisors LLC is the largest reported institutional holder of QURE, with approximately 5,959,595 shares worth $0.10B as of Q1 2026.
Yes β 4 widely-followed marquee investors appear among the top 25 institutional holders of QURE, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, TWO SIGMA INVESTMENTS, LP, CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for QURE is 45 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
46 institutions opened new positions in QURE during Q1 2026, while 62 fully exited. 39 added to existing positions and 114 trimmed.
QURE institutional ownership fell by 28.40 percentage points quarter-over-quarter, with a net change of -16 holders.
The top 10 institutions account for 48.5% of all reported 13F value in QURE, and the top 25 account for 75.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
uniQure N.V. (QURE) Institutional Ownership