Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in QURE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Avoro Capital Advisors LLC | 6.7M | $309.9M | +12.9% | 9.699% | 2.78% |
| 2 | JPMORGAN CHASE & CO | 4.9M | $230.8M | +71.5% | 7.018% | 0.01% |
| 3 | RTW INVESTMENTS, LP | 3.9M | $181.5M | +52.4% | 5.682% | 1.55% |
| 4 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3.5M | $161.0M | -4.1% | 5.038% | 0.01% |
| 5 | STATE STREET CORP | 2.9M | $133.8M | +28.5% | 4.186% | 0.00% |
| 6 | Aberdeen Group plc | 2.8M | $131.2M | -46.3% | 4.106% | 0.18% |
| 7 | CITADEL ADVISORS LLC | 2.5M | $115.5M | +36.9% | 3.614% | 0.01% |
| 8 | JANE STREET GROUP, LLC | 2.2M | $103.6M | +113.2% | 3.243% | 0.01% |
| 9 | BlackRock, Inc. | 1.9M | $86.5M | +8.3% | 2.707% | 0.00% |
| 10 | Caption Management, LLC | 1.8M | $84.9M | -27.0% | 2.658% | 0.40% |
| 11 | ORBIMED ADVISORS LLC | 1.8M | $83.3M | -15.4% | 2.606% | 1.54% |
| 12 | JENNISON ASSOCIATES LLC | 1.6M | $71.9M | +26.6% | 2.251% | 0.04% |
| 13 | Boxer Capital Management, LLC | 1.5M | $69.2M | +127.1% | 2.167% | 5.21% |
| 14 | GOLDMAN SACHS GROUP INC | 1.5M | $68.0M | +16.8% | 2.128% | 0.01% |
| 15 | TWO SIGMA INVESTMENTS, LP | 1.5M | $67.3M | -45.4% | 2.108% | 0.05% |
| 16 | Two Seas Capital LP | 1.4M | $66.4M | +10.9% | 2.078% | 1.31% |
| 17 | Nantahala Capital Management, LLC | 1.4M | $65.3M | -50.0% | 2.043% | 1.08% |
| 18 | FMR LLC | 1.3M | $58.5M | -27.2% | 1.831% | 0.00% |
| 19 | MAK CAPITAL ONE LLC | 1.2M | $56.7M | +179.3% | 1.776% | 7.95% |
| 20 | MPM BioImpact LLC | 1.2M | $56.5M | -10.5% | 1.767% | 3.44% |
| 21 | TUDOR INVESTMENT CORP ET AL | 1.1M | $49.8M | +170.0% | 1.559% | 0.07% |
| 22 | MORGAN STANLEY | 1.1M | $49.1M | +191.3% | 1.538% | 0.00% |
| 23 | Vestal Point Capital, LP | 935K | $43.1M | +160.5% | 1.348% | 1.01% |
| 24 | MAVERICK CAPITAL LTD | 925K | $42.6M | +32.6% | 1.334% | 0.38% |
| 25 | Fiera Capital Corp | 909K | $41.9M | +11.3% | 1.311% | 0.15% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in QURE — a direct measure of their conviction.
Filings activity in QURE during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new QURE position in Q2 2026
Institutions that fully closed their QURE position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 261 | +17% | 111.19% | 9.34 pp | $3.54B | +190% |
| Q1 2026 | 223 | 1.8% | 120.53% | +7.05 pp | $1.22B | 27% |
| Q4 2025 | 227 | +1.8% | 113.48% | +12.09 pp | $1.67B | 54% |
| Q3 2025 | 223 | +59% | 101.39% | +0.64 pp | $3.60B | +300% |
| Q2 2025 | 140 | +5.3% | 100.75% | +9.11 pp | $901M | +72% |
| Q1 2025 | 133 | 0.7% | 91.64% | +3.28 pp | $523M | 30% |
| Q4 2024 | 134 | +4.7% | 88.36% | +6.62 pp | $752M | +286% |
| Q3 2024 | 128 | — | 81.74% | — | $195M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying QURE stock.
Based on Q2 2026 13F filings, institutional ownership of uniQure N.V. stands at 111.2%, held across 261 reporting institutions.
Avoro Capital Advisors LLC is the largest reported institutional holder of QURE, with approximately 6,727,777 shares worth $0.31B as of Q2 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of QURE, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC, JANE STREET GROUP, LLC, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for QURE is 59 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
83 institutions opened new positions in QURE during Q2 2026, while 47 fully exited. 163 added to existing positions and 9 trimmed.
QURE institutional ownership fell by 9.34 percentage points quarter-over-quarter, with a net change of +38 holders.
The top 10 institutions account for 43.4% of all reported 13F value in QURE, and the top 25 account for 68.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
uniQure N.V. (QURE) Institutional Ownership