Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SABS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Vivo Capital, LLC | 11.4M | $43.7M | 0.0% | 21.322% | 3.65% |
| 2 | Caligan Partners LP | 8.0M | $30.5M | β | 14.876% | 2.12% |
| 3 | PERCEPTIVE ADVISORS LLC | 6.4M | $24.6M | +700.8% | 12.009% | 0.49% |
| 4 | COMMODORE CAPITAL LP | 4.4M | $16.9M | 0.0% | 8.218% | 0.98% |
| 5 | RA CAPITAL MANAGEMENT, L.P. | 4.4M | $16.9M | 0.0% | 8.218% | 0.18% |
| 6 | BALYASNY ASSET MANAGEMENT LLC | 3.8M | $14.4M | +690.9% | 7.021% | 0.05% |
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 3.4M | $13.0M | β | 6.359% | 0.02% |
| 8 | MILLENNIUM MANAGEMENT LLC | 3.0M | $11.6M | +835.8% | 5.662% | 0.01% |
| 9 | Woodline Partners LP | 2.9M | $10.9M | +0.0% | 5.325% | 0.04% |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC | 2.5M | $9.6M | β | 4.656% | 0.00% |
| 11 | Spruce Street Capital LP | 2.2M | $8.4M | 0.0% | 4.105% | 2.02% |
| 12 | Sessa Capital IM, L.P. | 2.2M | $8.4M | 0.0% | 4.105% | 0.16% |
| 13 | BOOTHBAY FUND MANAGEMENT, LLC | 1.5M | $5.7M | β | 2.766% | 0.14% |
| 14 | AMERIPRISE FINANCIAL INC | 1.5M | $5.7M | +420.4% | 2.756% | 0.00% |
| 15 | Ensign Peak Advisors, Inc | 1.4M | $5.3M | β | 2.568% | 0.01% |
| 16 | Soleus Capital Management, L.P. | 1.1M | $4.0M | β | 1.961% | 0.16% |
| 17 | Propel Bio Management, LLC | 1.0M | $3.9M | +55.1% | 1.891% | 2.45% |
| 18 | Jefferies Financial Group Inc. | 903K | $3.5M | +55.6% | 1.686% | 0.02% |
| 19 | Blackstone Inc | 860K | $3.3M | -59.9% | 1.606% | 0.01% |
| 20 | ExodusPoint Capital Management, LP | 769K | $2.9M | +792.6% | 1.435% | 0.03% |
| 21 | Affinity Asset Advisors, LLC | 575K | $2.2M | β | 1.074% | 0.13% |
| 22 | Monashee Investment Management LLC | 500K | $1.9M | β | 0.934% | 1.04% |
| 23 | MARSHALL WACE, LLP | 464K | $1.8M | +96.2% | 0.866% | 0.00% |
| 24 | DV Trading LLC | 400K | $1.5M | β | 0.747% | 0.04% |
| 25 | AWM Investment Company, Inc. | 400K | $1.5M | +100.0% | 0.747% | 0.17% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SABS β a direct measure of their conviction.
Filings activity in SABS during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new SABS position in Q1 2026
Institutions that fully closed their SABS position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 75 | +56% | 148.47% | +72.30 pp | $265M | +95% |
| Q4 2025 | 48 | +41% | 76.17% | +44.63 pp | $136M | +142% |
| Q3 2025 | 34 | +31% | 31.54% | +29.66 pp | $56M | +1581% |
| Q2 2025 | 26 | 3.7% | 1.88% | +0.22 pp | $3M | +13% |
| Q1 2025 | 27 | +3.8% | 1.66% | 3.96 pp | $3M | 70% |
| Q4 2024 | 26 | +0.0% | 5.62% | +0.89 pp | $10M | +19% |
| Q3 2024 | 26 | +13% | 4.73% | 0.67 pp | $8M | 12% |
| Q2 2024 | 23 | β | 5.40% | β | $10M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SABS stock.
Based on Q1 2026 13F filings, institutional ownership of SAB Biotherapeutics, Inc. stands at 148.5%, held across 75 reporting institutions.
Vivo Capital, LLC is the largest reported institutional holder of SABS, with approximately 11,420,000 shares worth $0.04B as of Q1 2026.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of SABS, including MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for SABS is 73 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
34 institutions opened new positions in SABS during Q1 2026, while 7 fully exited. 35 added to existing positions and 6 trimmed.
SABS institutional ownership rose by 72.30 percentage points quarter-over-quarter, with a net change of +27 holders.
The top 10 institutions account for 72.6% of all reported 13F value in SABS, and the top 25 account for 95.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.