Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in SABS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Caligan Partners LP | 8.0M | $31.1M | 0.0% | 9.990% | 1.46% |
| 2 | Vivo Capital, LLC | 7.3M | $28.5M | -36.1% | 9.153% | 2.60% |
| 3 | PERCEPTIVE ADVISORS LLC | 6.6M | $25.8M | +3.0% | 8.310% | 0.39% |
| 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 6.4M | $25.0M | +88.1% | 8.032% | 0.04% |
| 5 | RA CAPITAL MANAGEMENT, L.P. | 4.4M | $17.2M | 0.0% | 5.519% | 0.15% |
| 6 | BALYASNY ASSET MANAGEMENT L.P. | 3.8M | $14.7M | 0.0% | 4.715% | 0.02% |
| 7 | BlackRock, Inc. | 3.1M | $12.0M | +917.5% | 3.844% | 0.00% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 3.0M | $11.6M | +19.2% | 3.728% | 0.00% |
| 9 | Commodore Capital LP | 2.9M | $11.2M | -34.8% | 3.599% | 0.67% |
| 10 | MILLENNIUM MANAGEMENT LLC | 2.7M | $10.7M | -9.3% | 3.447% | 0.00% |
| 11 | Spruce Street Capital LP | 2.2M | $8.6M | 0.0% | 2.757% | 1.68% |
| 12 | Sessa Capital IM, L.P. | 2.2M | $8.6M | 0.0% | 2.757% | 0.14% |
| 13 | Affinity Asset Advisors, LLC | 1.5M | $5.9M | +165.2% | 1.912% | 0.27% |
| 14 | BOOTHBAY FUND MANAGEMENT, LLC | 1.5M | $5.8M | 0.0% | 1.858% | 0.08% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $5.0M | +322.9% | 1.601% | 0.00% |
| 16 | Woodline Partners LP | 1.2M | $4.6M | -58.6% | 1.480% | 0.01% |
| 17 | Ensign Peak Advisors, Inc | 1.2M | $4.6M | -14.8% | 1.470% | 0.01% |
| 18 | Propel Bio Management, LLC | 1.1M | $4.2M | +6.3% | 1.350% | 2.20% |
| 19 | Soleus Capital Management, L.P. | 900K | $3.5M | -14.3% | 1.129% | 0.12% |
| 20 | Seven Fleet Capital Management LP | 736K | $2.9M | +636.1% | 0.923% | 0.47% |
| 21 | AMERIPRISE FINANCIAL INC | 611K | $2.4M | -58.6% | 0.766% | 0.00% |
| 22 | STATE STREET CORP | 531K | $2.1M | +615.1% | 0.666% | 0.00% |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 467K | $1.8M | +917.2% | 0.586% | 0.00% |
| 24 | DV EQUITIES, LLC | 400K | $1.6M | — | 0.502% | 0.22% |
| 25 | AWM Investment Company, Inc. | 375K | $1.5M | -6.3% | 0.470% | 0.13% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in SABS — a direct measure of their conviction.
Filings activity in SABS during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 87 | +10% | 86.25% | 9.66 pp | $268M | +0.9% |
| Q1 2026 | 79 | +65% | 95.91% | +16.00 pp | $266M | +95% |
| Q4 2025 | 48 | +41% | 79.91% | +18.14 pp | $136M | +142% |
| Q3 2025 | 34 | +31% | 61.77% | +59.36 pp | $56M | +1581% |
| Q2 2025 | 26 | 3.7% | 2.41% | 0.36 pp | $3M | +13% |
| Q1 2025 | 27 | +3.8% | 2.77% | 0.53 pp | $3M | 70% |
| Q4 2024 | 26 | +0.0% | 3.30% | 0.64 pp | $10M | +19% |
| Q3 2024 | 26 | — | 3.94% | — | $8M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SABS stock.
Based on Q2 2026 13F filings, institutional ownership of SAB Biotherapeutics, Inc. stands at 86.3%, held across 87 reporting institutions.
Caligan Partners LP is the largest reported institutional holder of SABS, with approximately 7,967,207 shares worth $0.03B as of Q2 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of SABS, including MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for SABS is 47 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
28 institutions opened new positions in SABS during Q2 2026, while 21 fully exited. 41 added to existing positions and 16 trimmed.
SABS institutional ownership fell by 9.66 percentage points quarter-over-quarter, with a net change of +8 holders.
The top 10 institutions account for 70.0% of all reported 13F value in SABS, and the top 25 account for 93.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
SAB Biotherapeutics, Inc. (SABS) Institutional Ownership