Sionna Therapeutics, Inc. (SION) Stock Price History
Historical prices from 2025 to 2026
- 1M
- -1.6%
- 3M
- +11.1%
- YTD
- +7.6%
- 1Y
- +184.4%
- 3Y
- +19.0%
- 5Y
- +11.0%
Loading 10-year price history...
SION Historical Performance
SION Annual Returns
Year-by-year price performance · 2025–2026
- 2025 annual price return
- +64.6%
- 2026 annual price return
- -6.8%
SION Stock Price Trajectory (2025–2026)
As of June 28, 2026, Sionna Therapeutics, Inc. (SION) trades at $42.18, representing a +184.4% return over the past year. The stock has delivered a +64.4% total return over five years (+11.0% CAGR), reflecting significant long-term value creation.
The stock reached its all-time high of $48.43 on May 11, 2026. From this peak, SION has corrected -12.9%, currently trading 12% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers VRTX (+10.8% 1Y), ABBV (+34.7% 1Y), and PTCT (+70.4% 1Y), SION has outperformed the peer group average. Compare SION vs VRTX →
SION Historical Price Data · from 2025
Rows 1–50 of 348| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-26 | 42.56 | 44.03 | 40.69 | 42.18 | 0 | -1.38% |
| 2026-06-25 | 41.09 | 44.25 | 40.44 | 42.77 | 469K | +4.09% |
| 2026-06-24 | 39.81 | 41.25 | 39.18 | 41.09 | 544K | +3.06% |
| 2026-06-23 | 38.93 | 42.30 | 37.28 | 39.87 | 528K | +2.68% |
| 2026-06-22 | 37.89 | 40.02 | 37.87 | 38.83 | 396K | +4.10% |
| 2026-06-18 | 38.28 | 38.55 | 36.63 | 37.30 | 596K | +1.55% |
| 2026-06-17 | 34.81 | 37.11 | 33.98 | 36.73 | 402K | +5.70% |
| 2026-06-16 | 36.01 | 36.20 | 34.42 | 34.75 | 352K | -3.47% |
| 2026-06-15 | 36.54 | 37.82 | 35.53 | 36.00 | 86K | +0.22% |
| 2026-06-12 | 36.05 | 37.17 | 35.57 | 35.92 | 189K | -0.36% |
| 2026-06-11 | 34.20 | 36.84 | 33.98 | 36.05 | 395K | +5.94% |
| 2026-06-10 | 33.44 | 35.29 | 32.93 | 34.03 | 316K | +1.01% |
| 2026-06-09 | 32.58 | 35.26 | 32.36 | 33.69 | 313K | +0.54% |
| 2026-06-08 | 35.29 | 35.44 | 32.26 | 33.51 | 422K | -5.26% |
| 2026-06-05 | 37.81 | 37.95 | 35.25 | 35.37 | 453K | -6.38% |
| 2026-06-04 | 36.98 | 39.33 | 36.60 | 37.78 | 348K | +2.94% |
| 2026-06-03 | 36.50 | 37.37 | 35.66 | 36.70 | 319K | +0.60% |
| 2026-06-02 | 41.89 | 41.91 | 36.46 | 36.48 | 470K | -10.81% |
| 2026-06-01 | 41.87 | 42.07 | 38.93 | 40.90 | 469K | -4.48% |
| 2026-05-29 | 42.96 | 43.77 | 42.15 | 42.82 | 567K | +0.05% |
| 2026-05-28 | 43.43 | 44.61 | 42.39 | 42.80 | 413K | -1.45% |
| 2026-05-27 | 43.46 | 44.49 | 42.95 | 43.43 | 185K | +1.28% |
| 2026-05-26 | 42.11 | 43.16 | 40.53 | 42.88 | 184K | +4.25% |
| 2026-05-22 | 41.81 | 43.41 | 40.81 | 41.13 | 169K | -1.49% |
| 2026-05-21 | 39.19 | 41.81 | 38.65 | 41.75 | 227K | +5.70% |
| 2026-05-20 | 38.39 | 39.71 | 36.90 | 39.50 | 389K | +4.83% |
| 2026-05-19 | 38.97 | 39.19 | 37.48 | 37.68 | 312K | -3.98% |
| 2026-05-18 | 41.46 | 41.46 | 38.16 | 39.24 | 321K | -2.44% |
| 2026-05-15 | 41.87 | 42.55 | 40.07 | 40.22 | 269K | -5.96% |
| 2026-05-14 | 42.70 | 44.22 | 41.54 | 42.77 | 337K | -0.56% |
| 2026-05-13 | 40.78 | 43.54 | 40.23 | 43.01 | 524K | +5.06% |
| 2026-05-12 | 45.07 | 46.07 | 40.77 | 40.94 | 503K | -11.00% |
| 2026-05-11 | 45.10 | 48.43 | 44.66 | 46.00 | 667K | +4.00% |
| 2026-05-08 | 43.80 | 45.10 | 43.35 | 44.23 | 381K | +2.12% |
| 2026-05-07 | 43.35 | 45.33 | 42.41 | 43.31 | 776K | +0.05% |
| 2026-05-06 | 41.69 | 43.85 | 40.43 | 43.29 | 308K | +5.66% |
| 2026-05-05 | 42.68 | 43.73 | 40.42 | 40.97 | 320K | +1.29% |
| 2026-05-04 | 38.64 | 41.45 | 38.64 | 40.45 | 233K | +3.32% |
| 2026-05-01 | 38.66 | 40.27 | 38.07 | 39.15 | 206K | +1.16% |
| 2026-04-30 | 37.82 | 38.92 | 37.67 | 38.70 | 240K | +3.39% |
| 2026-04-29 | 39.01 | 40.30 | 36.50 | 37.43 | 280K | -5.46% |
| 2026-04-28 | 39.68 | 40.47 | 38.58 | 39.59 | 392K | +0.97% |
| 2026-04-27 | 38.02 | 42.21 | 37.97 | 39.21 | 619K | +2.89% |
| 2026-04-24 | 38.35 | 38.61 | 35.11 | 38.11 | 507K | -0.63% |
| 2026-04-23 | 43.08 | 44.12 | 37.80 | 38.35 | 445K | -11.23% |
| 2026-04-22 | 41.81 | 43.63 | 41.72 | 43.20 | 357K | +3.37% |
| 2026-04-21 | 43.01 | 43.41 | 41.34 | 41.79 | 350K | -1.99% |
| 2026-04-20 | 43.54 | 44.69 | 41.98 | 42.64 | 447K | -2.07% |
| 2026-04-17 | 46.13 | 46.46 | 43.31 | 43.54 | 507K | -3.76% |
| 2026-04-16 | 44.41 | 46.03 | 42.86 | 45.24 | 814K | +0.33% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SION — Frequently Asked Questions
Quick answers to the most common questions about buying SION stock.
How has SION stock performed recently?
SION returned +184.4% over the past year, beating its 5-year annualized CAGR of +11.0%. The stock trades above its 200-day moving average, confirming the uptrend.
What is SION's all-time high price?
Sionna Therapeutics, Inc. reached $48.43 on 2026-05-11. The 52-week high is $48.43. Current 1-year return of +184.4% places the stock closer to historical peaks.
Where can I download SION historical price data?
This page provides SION daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2025-2026, downloadable in CSV format.