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Vertex Pharmaceuticals Incorporated (VRTX) Earnings History

Annual and quarterly earnings data from 1991 to 2025

TTM Net Income
$3.68B
Profitable
TTM EPS
$14.27
Diluted
YoY EPS Growth
+8.4%
Solid
Net Margin
0.3%
Profitability
Operating Margin0.4%
Gross Margin0.9%
ROE0.2%
ROA0.2%
Highest Annual Net Income$3.95B (2025)
Highest Quarterly EPS$5.97 (Q4 2018)
Consecutive Profitable Years1 years
Q3 2025
Net Income$1.08B
EPS$4.20
QoQ Growth+4.8%Solid

Loading earnings history...

EPS Growth Rates (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
+6.1%
Solid
5-Year
+8.3%
Solid
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202586.2%39.1%32.9%
202486.1%-2.1%-4.9%
202387.2%38.8%36.7%
202287.9%48.2%37.2%
202188.1%36.7%30.9%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Vertex Pharmaceuticals Incorporated (VRTX) Earnings Overview

As of March 1, 2026, Vertex Pharmaceuticals Incorporated (VRTX) reported trailing twelve-month net income of $3.68B, reflecting +8.4% year-over-year growth. The company earned $14.27 per diluted share over the past four quarters, with a net profit margin of 0.3%.

Looking at the long-term picture, VRTX's 5-year EPS compound annual growth rate (CAGR) stands at +8.3%, showing solid earnings momentum. The company achieved its highest annual net income of $3.95B in fiscal 2025, representing a new all-time high.

Vertex Pharmaceuticals Incorporated maintains positive profitability with a gross margin of 0.9%, operating margin of 0.4%, and net margin of 0.3%. The company continues to generate positive earnings from operations. View revenue history →

Compared to industry peers including AGIO (-$401M net income, -7.6% margin), ASND (-$228M net income, -0.3% margin), BBIO (-$729M net income, -1.5% margin), VRTX has outperformed on profitability metrics. Compare VRTX vs AGIO →

Peer Comparison

Earnings metrics vs industry competitors

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
VRTXCurrent
$3.7B$14.270.3%0.2%+8.4%—
AGIO
-$401M$-6.90-7.6%-0.3%-1.6%
ASND
-$228M$-3.71-0.3%-+0.4%
BBIO
-$729M$-3.70-1.5%--0.3%
BMRN
$349M$1.770.1%0.1%+11.9%
COGT
-$329M$-4.87--0.7%-0.0%
Best in group
Lowest in group

Historical Data

35 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025$3.95B+838.1%$4.69B$15.3232.9%39.1%
2024-$536M-114.8%-$233M$-2.08-4.9%-2.1%
2023$3.62B+9.0%$3.83B$13.8936.7%38.8%
2022$3.32B+41.8%$4.31B$12.8237.2%48.2%
2021$2.34B-13.6%$2.78B$9.0130.9%36.7%
2020$2.71B+130.4%$2.86B$10.2943.7%46.0%
2019$1.18B-43.9%$1.20B$4.5128.3%28.8%
2018$2.10B+695.8%$635M$8.0968.8%20.8%
2017$263M+335.1%$123M$1.0410.6%5.0%
2016-$112M+79.9%$10M$-0.46-6.6%0.6%

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Compare VRTX vs AGIO

See how VRTX stacks up against sector leader Agios Pharmaceuticals, Inc..

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Frequently Asked Questions

Is VRTX growing earnings?

VRTX EPS stands at $14.27, with +8.4% growth matching the 5-year CAGR of +8.3%. TTM net income is $3.7B. Earnings trajectory remains consistent.

What are VRTX's profit margins?

Vertex Pharmaceuticals Incorporated net margin is +0.3%, with operating margin at +0.4%. Below-average margins reflect competitive or cost pressures.

How consistent are VRTX's earnings?

VRTX earnings data spans 1991-2025. The current earnings trend is +8.4% YoY. Historical data enables comparison across business cycles.

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Earnings Over Time

Net income and EPS trends