Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ZLAB held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LP | 6.6M | $123.7M | -5.5% | 5.939% | 1.23% |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 5.7M | $107.4M | — | 5.156% | 1.14% |
| 3 | Frazier Life Sciences Management, L.P. | 1.9M | $35.8M | 0.0% | 1.719% | 0.92% |
| 4 | CITADEL ADVISORS LLC | 1.7M | $32.4M | -1.6% | 1.556% | 0.02% |
| 5 | BAMCO INC /NY/ | 1.7M | $31.2M | +17.0% | 1.498% | 0.09% |
| 6 | ADAR1 Capital Management, LLC | 1.4M | $26.8M | +14.3% | 1.288% | 1.68% |
| 7 | FMR LLC | 1.3M | $23.7M | -12.4% | 1.141% | 0.00% |
| 8 | BlackRock, Inc. | 865K | $16.3M | +36.2% | 0.782% | 0.00% |
| 9 | Rock Springs Capital Management LP | 815K | $15.3M | +0.4% | 0.736% | 0.90% |
| 10 | UBS Group AG | 504K | $9.5M | -71.7% | 0.456% | 0.00% |
| 11 | B Group, Inc. | 451K | $8.5M | +12.7% | 0.407% | 6.28% |
| 12 | SCHRODER INVESTMENT MANAGEMENT GROUP | 393K | $7.0M | +31.1% | 0.355% | 0.01% |
| 13 | NAN FUNG TRINITY (HK) Ltd | 346K | $6.5M | +28.3% | 0.313% | 0.72% |
| 14 | TWO SIGMA INVESTMENTS, LP | 310K | $5.8M | +949.1% | 0.280% | 0.00% |
| 15 | SUPERSTRING CAPITAL MANAGEMENT LP | 276K | $5.2M | +40.1% | 0.249% | 3.71% |
| 16 | AMERIPRISE FINANCIAL INC | 244K | $4.6M | +34.5% | 0.220% | 0.00% |
| 17 | abrdn plc | 238K | $4.5M | — | 0.215% | 0.01% |
| 18 | NEXTBio Capital Management LP | 183K | $3.4M | +12.2% | 0.166% | 1.60% |
| 19 | DIMENSIONAL FUND ADVISORS LP | 174K | $3.3M | +0.2% | 0.157% | 0.00% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 145K | $2.7M | -1.8% | 0.131% | 0.00% |
| 21 | Privium Fund Management B.V. | 132K | $2.5M | 0.0% | 0.119% | 0.52% |
| 22 | STATE STREET CORP | 119K | $2.2M | -12.9% | 0.107% | 0.00% |
| 23 | BNP Paribas Asset Management Holding S.A. | 117K | $2.2M | +77.1% | 0.105% | 0.00% |
| 24 | GOLDMAN SACHS GROUP INC | 111K | $2.1M | -26.0% | 0.100% | 0.00% |
| 25 | Walleye Capital LLC | 95K | $1.8M | -74.6% | 0.086% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ZLAB — a direct measure of their conviction.
Filings activity in ZLAB during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 94 | 22% | 26.75% | +0.86 pp | $505M | +3.3% |
| Q4 2025 | 121 | 9.7% | 25.89% | 34.29 pp | $489M | 57% |
| Q3 2025 | 134 | 13% | 60.18% | 139.81 pp | $1.14B | 72% |
| Q2 2025 | 154 | 1.9% | 199.99% | +102.33 pp | $4.02B | +118% |
| Q1 2025 | 157 | +24% | 97.66% | +23.64 pp | $1.85B | +32% |
| Q4 2024 | 127 | +28% | 74.02% | +21.53 pp | $1.40B | +41% |
| Q3 2024 | 99 | 1.0% | 52.49% | +18.15 pp | $992M | +53% |
| Q2 2024 | 100 | — | 34.34% | — | $649M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ZLAB stock.
Based on Q1 2026 13F filings, institutional ownership of Zai Lab Limited stands at 26.8%, held across 94 reporting institutions.
RTW INVESTMENTS, LP is the largest reported institutional holder of ZLAB, with approximately 6,574,032 shares worth $0.12B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of ZLAB, including CITADEL ADVISORS LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for ZLAB is 53 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
18 institutions opened new positions in ZLAB during Q1 2026, while 45 fully exited. 41 added to existing positions and 35 trimmed.
ZLAB institutional ownership rose by 0.86 percentage points quarter-over-quarter, with a net change of -27 holders.
The top 10 institutions account for 83.5% of all reported 13F value in ZLAB, and the top 25 account for 95.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Zai Lab Limited (ZLAB) Institutional Ownership