| 4 |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
| 6.4M |
| $517.7M |
| -11.1% |
| 4.509% |
| 0.02% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 6.1M | $498.1M | +1.3% | 4.338% | 0.01% |
| 6 | STATE STREET CORP | 5.7M | $464.2M | -12.3% | 4.043% | 0.01% |
| 7 | NORGES BANK | 3.9M | $317.6M | — | 2.766% | 0.03% |
| 8 | Invesco Ltd. | 3.9M | $316.6M | +18.4% | 2.757% | 0.03% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 3.5M | $298.8M | -17.5% | 2.506% | 0.02% |
| 10 | FRED ALGER MANAGEMENT, LLC | 3.3M | $269.1M | -1.2% | 2.344% | 0.90% |
| 11 | BAKER BROS. ADVISORS LP | 2.0M | $162.4M | 0.0% | 1.415% | 0.81% |
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.9M | $153.9M | +2.8% | 1.341% | 0.01% |
| 13 | Siren, L.L.C. | 1.7M | $139.8M | +6.2% | 1.218% | 2.83% |
| 14 | Vestal Point Capital, LP | 1.6M | $128.4M | -30.8% | 1.118% | 3.00% |
| 15 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1.4M | $113.2M | -11.7% | 0.986% | 1.18% |
| 16 | FIRST TRUST ADVISORS LP | 1.4M | $110.3M | +807.1% | 0.961% | 0.06% |
| 17 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.4M | $110.1M | +13.5% | 0.959% | 0.64% |
| 18 | Jupiter Topco LLC | 1.2M | $99.6M | — | 0.867% | 0.04% |
| 19 | NORTHERN TRUST CORP | 1.2M | $97.2M | -28.0% | 0.847% | 0.01% |
| 20 | DIMENSIONAL FUND ADVISORS LP | 1.2M | $96.3M | +94.2% | 0.839% | 0.02% |
| 21 | GOLDMAN SACHS GROUP INC | 1.2M | $93.7M | -33.9% | 0.816% | 0.01% |
| 22 | BANK OF AMERICA CORP /DE/ | 1.1M | $92.9M | +7.1% | 0.809% | 0.01% |
| 23 | Hood River Capital Management LLC | 1.1M | $91.4M | +6.1% | 0.796% | 0.66% |
| 24 | Holocene Advisors, LP | 1.1M | $90.2M | — | 0.785% | 0.20% |
| 25 | MORGAN STANLEY | 1.1M | $88.4M | +12.9% | 0.770% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ARWR — a direct measure of their conviction.
| 74.36% |
| 5.18 pp |
| $1.26B |
| 44% |
| Q4 2024 | 269 | +1.1% | 79.54% | +3.23 pp | $2.25B | +29% |
| Q3 2024 | 266 | — | 76.31% | — | $1.74B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
118 institutions opened new positions in ARWR during Q2 2026, while 56 fully exited. 305 added to existing positions and 69 trimmed.
ARWR institutional ownership fell by 1.18 percentage points quarter-over-quarter, with a net change of +68 holders.
The top 10 institutions account for 56.2% of all reported 13F value in ARWR, and the top 25 account for 73.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Arrowhead Pharmaceuticals, Inc. (ARWR) Institutional Ownership