Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ARWR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 18.2M | $1.14B | -14.8% | 12.894% | 0.02% |
| 2 | Avoro Capital Advisors LLC | 10.7M | $670.9M | +0.7% | 7.596% | 6.86% |
| 3 | FMR LLC | 7.3M | $455.6M | +11.4% | 5.159% | 0.02% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 7.1M | $448.1M | — | 5.073% | 0.02% |
| 5 | STATE STREET CORP | 6.5M | $407.3M | +1.4% | 4.612% | 0.01% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 6.0M | $378.2M | — | 4.283% | 0.01% |
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 4.3M | $274.5M | +31.1% | 3.038% | 0.02% |
| 8 | FRED ALGER MANAGEMENT, LLC | 3.3M | $209.6M | +82.3% | 2.373% | 0.92% |
| 9 | Invesco Ltd. | 3.3M | $205.7M | +498.9% | 2.329% | 0.03% |
| 10 | Vestal Point Capital, LP | 2.3M | $142.6M | +152.8% | 1.615% | 3.99% |
| 11 | BAKER BROS. ADVISORS LP | 2.0M | $124.9M | -8.4% | 1.415% | 0.72% |
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.8M | $115.1M | +50.5% | 1.304% | 0.01% |
| 13 | GOLDMAN SACHS GROUP INC | 1.7M | $109.1M | +2.5% | 1.235% | 0.01% |
| 14 | NORTHERN TRUST CORP | 1.7M | $103.8M | +23.0% | 1.175% | 0.01% |
| 15 | Siren, L.L.C. | 1.6M | $101.3M | +7.7% | 1.147% | 2.81% |
| 16 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 1.6M | $98.6M | -14.2% | 1.117% | 1.16% |
| 17 | JANUS HENDERSON GROUP PLC | 1.4M | $90.1M | +12.2% | 1.020% | 0.04% |
| 18 | UBS Group AG | 1.3M | $83.8M | +35.4% | 0.949% | 0.01% |
| 19 | UBS ASSET MANAGEMENT AMERICAS INC | 1.3M | $83.5M | +5.6% | 0.945% | 0.02% |
| 20 | Pictet Asset Management Holding SA | 1.3M | $79.6M | +23.8% | 0.904% | 0.08% |
| 21 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.2M | $74.7M | -11.9% | 0.846% | 0.01% |
| 22 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.2M | $74.6M | -32.7% | 0.845% | 0.55% |
| 23 | Fisher Asset Management, LLC | 1.1M | $69.8M | -15.1% | 0.791% | 0.02% |
| 24 | BANK OF AMERICA CORP /DE/ | 1.1M | $66.7M | +71.1% | 0.756% | 0.00% |
| 25 | Hood River Capital Management LLC | 1.1M | $66.2M | — | 0.750% | 0.66% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ARWR — a direct measure of their conviction.
Filings activity in ARWR during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 423 | +7.4% | 70.43% | 3.15 pp | $7.39B | 4.3% |
| Q4 2025 | 394 | +34% | 73.58% | +37.15 pp | $7.72B | +102% |
| Q3 2025 | 294 | +6.9% | 36.43% | +20.78 pp | $3.82B | +133% |
| Q2 2025 | 275 | +7.8% | 15.65% | +3.65 pp | $1.64B | +30% |
| Q1 2025 | 255 | 5.2% | 12.00% | 9.40 pp | $1.26B | 44% |
| Q4 2024 | 269 | +1.1% | 21.40% | +4.81 pp | $2.25B | +29% |
| Q3 2024 | 266 | +0.4% | 16.59% | 5.85 pp | $1.74B | 26% |
| Q2 2024 | 265 | — | 22.44% | — | $2.36B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ARWR stock.
Based on Q1 2026 13F filings, institutional ownership of Arrowhead Pharmaceuticals, Inc. stands at 70.4%, held across 423 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of ARWR, with approximately 18,161,519 shares worth $1.14B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of ARWR, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, Fisher Asset Management, LLC.
Our composite Smart Money Score for ARWR is 51 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
104 institutions opened new positions in ARWR during Q1 2026, while 75 fully exited. 139 added to existing positions and 178 trimmed.
ARWR institutional ownership fell by 3.15 percentage points quarter-over-quarter, with a net change of +29 holders.
The top 10 institutions account for 58.6% of all reported 13F value in ARWR, and the top 25 account for 76.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Arrowhead Pharmaceuticals, Inc. (ARWR) Institutional Ownership