Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in AXSM held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 3.1M | $759.7M | -20.7% | 6.031% | 0.01% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.0M | $485.5M | -3.6% | 3.855% | 0.02% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | $481.0M | +1.4% | 3.819% | 0.01% |
| 4 | Invesco Ltd. | 1.7M | $409.2M | +28.8% | 3.248% | 0.03% |
| 5 | FMR LLC | 1.5M | $376.7M | -1.8% | 2.991% | 0.02% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 967K | $236.8M | -16.8% | 1.879% | 0.01% |
| 7 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 907K | $222.1M | +104.1% | 1.763% | 0.02% |
| 8 | MORGAN STANLEY | 804K | $196.8M | +68.7% | 1.563% | 0.01% |
| 9 | STATE STREET CORP | 786K | $192.3M | -20.4% | 1.527% | 0.00% |
| 10 | JANE STREET GROUP, LLC | 750K | $183.5M | +282.0% | 1.457% | 0.02% |
| 11 | Deep Track Capital, LP | 700K | $171.3M | -36.4% | 1.360% | 2.49% |
| 12 | TWO SIGMA INVESTMENTS, LP | 680K | $166.4M | +108.3% | 1.321% | 0.12% |
| 13 | FRANKLIN RESOURCES INC | 668K | $163.6M | +52.4% | 1.299% | 0.04% |
| 14 | WELLINGTON MANAGEMENT GROUP LLP | 654K | $160.1M | -42.9% | 1.271% | 0.03% |
| 15 | D. E. Shaw & Co., Inc. | 653K | $159.9M | +7.6% | 1.270% | 0.08% |
| 16 | ALETHEA CAPITAL MANAGEMENT, LLC | 649K | $158.8M | -0.1% | 1.261% | 65.78% |
| 17 | MILLENNIUM MANAGEMENT LLC | 571K | $139.8M | +1023.3% | 1.110% | 0.05% |
| 18 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 539K | $132.0M | -33.6% | 1.048% | 0.20% |
| 19 | CITADEL ADVISORS LLC | 515K | $126.1M | +22.4% | 1.001% | 0.01% |
| 20 | NORGES BANK | 514K | $125.9M | β | 0.999% | 0.01% |
| 21 | FIRST TRUST ADVISORS LP | 482K | $118.0M | -16.5% | 0.937% | 0.07% |
| 22 | Point72 Asset Management, L.P. | 480K | $117.4M | +13.0% | 0.932% | 0.13% |
| 23 | Assenagon Asset Management S.A. | 455K | $111.3M | -47.5% | 0.884% | 0.07% |
| 24 | BANK OF AMERICA CORP /DE/ | 452K | $110.8M | -24.3% | 0.879% | 0.01% |
| 25 | AMERIPRISE FINANCIAL INC | 428K | $104.8M | +142.8% | 0.832% | 0.02% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in AXSM β a direct measure of their conviction.
Filings activity in AXSM during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 510 | +23% | 77.78% | +0.28 pp | $9.53B | +50% |
| Q1 2026 | 414 | +4.3% | 77.50% | 0.97 pp | $6.37B | 5.6% |
| Q4 2025 | 397 | +13% | 78.47% | +0.94 pp | $6.75B | +52% |
| Q3 2025 | 352 | +4.5% | 77.53% | 0.59 pp | $4.45B | +15% |
| Q2 2025 | 337 | 0.6% | 78.12% | +0.83 pp | $3.87B | 8.8% |
| Q1 2025 | 339 | +20% | 77.29% | 1.77 pp | $4.25B | +37% |
| Q4 2024 | 283 | +7.2% | 79.06% | +1.73 pp | $3.11B | 4.4% |
| Q3 2024 | 264 | β | 77.33% | β | $3.25B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying AXSM stock.
Based on Q2 2026 13F filings, institutional ownership of Axsome Therapeutics, Inc. stands at 77.8%, held across 510 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of AXSM, with approximately 3,103,708 shares worth $0.76B as of Q2 2026.
Yes β 6 widely-followed marquee investors appear among the top 25 institutional holders of AXSM, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, JANE STREET GROUP, LLC, TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC, CITADEL ADVISORS LLC.
Our composite Smart Money Score for AXSM is 85 out of 100 (Strong Smart Money). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
127 institutions opened new positions in AXSM during Q2 2026, while 37 fully exited. 313 added to existing positions and 57 trimmed.
AXSM institutional ownership rose by 0.28 percentage points quarter-over-quarter, with a net change of +96 holders.
The top 10 institutions account for 37.2% of all reported 13F value in AXSM, and the top 25 account for 58.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Axsome Therapeutics, Inc. (AXSM) Institutional Ownership