Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in AXSM held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 3.9M | $661.3M | -0.0% | 7.604% | 0.01% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.1M | $347.9M | — | 4.000% | 0.02% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 1.9M | $327.5M | — | 3.766% | 0.01% |
| 4 | FMR LLC | 1.6M | $264.9M | +32.6% | 3.045% | 0.01% |
| 5 | Invesco Ltd. | 1.3M | $219.3M | +1.9% | 2.522% | 0.03% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 1.2M | $196.6M | +15.1% | 2.260% | 0.01% |
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 1.1M | $193.6M | -6.3% | 2.226% | 0.04% |
| 8 | Deep Track Capital, LP | 1.1M | $185.9M | -4.3% | 2.138% | 3.84% |
| 9 | STATE STREET CORP | 987K | $166.8M | +3.0% | 1.918% | 0.01% |
| 10 | Assenagon Asset Management S.A. | 866K | $146.4M | +85.0% | 1.683% | 0.23% |
| 11 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 813K | $137.4M | -17.8% | 1.579% | 0.24% |
| 12 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 738K | $124.7M | +100.7% | 1.433% | 0.19% |
| 13 | ALETHEA CAPITAL MANAGEMENT, LLC | 649K | $109.7M | -2.9% | 1.261% | 56.28% |
| 14 | D. E. Shaw & Co., Inc. | 607K | $102.6M | +8.8% | 1.180% | 0.10% |
| 15 | BANK OF AMERICA CORP /DE/ | 598K | $101.1M | -3.2% | 1.162% | 0.01% |
| 16 | FIRST TRUST ADVISORS LP | 577K | $97.6M | +1230.2% | 1.122% | 0.07% |
| 17 | UBS Group AG | 547K | $92.5M | +54.0% | 1.063% | 0.01% |
| 18 | EVENTIDE ASSET MANAGEMENT, LLC | 520K | $87.8M | -9.0% | 1.010% | 1.45% |
| 19 | MORGAN STANLEY | 477K | $80.6M | -2.9% | 0.926% | 0.00% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 445K | $75.1M | -28.4% | 0.864% | 0.01% |
| 21 | FRANKLIN RESOURCES INC | 438K | $74.1M | +28.0% | 0.852% | 0.02% |
| 22 | Point72 Asset Management, L.P. | 425K | $71.8M | +901.8% | 0.825% | 0.10% |
| 23 | GOLDMAN SACHS GROUP INC | 421K | $71.2M | +40.1% | 0.819% | 0.01% |
| 24 | CITADEL ADVISORS LLC | 421K | $71.2M | — | 0.818% | 0.03% |
| 25 | Pictet Asset Management Holding SA | 416K | $70.3M | -4.6% | 0.808% | 0.08% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in AXSM — a direct measure of their conviction.
Filings activity in AXSM during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 400 | +2.8% | 46.85% | 3.30 pp | $6.15B | 6.6% |
| Q4 2025 | 389 | +12% | 50.15% | +16.37 pp | $6.59B | +48% |
| Q3 2025 | 346 | +2.7% | 33.78% | +4.28 pp | $4.44B | +15% |
| Q2 2025 | 337 | 0.6% | 29.50% | 2.85 pp | $3.87B | 8.8% |
| Q1 2025 | 339 | +20% | 32.35% | +8.68 pp | $4.25B | +37% |
| Q4 2024 | 283 | +7.2% | 23.67% | 1.08 pp | $3.11B | 4.4% |
| Q3 2024 | 264 | +6.9% | 24.75% | +0.34 pp | $3.25B | +1.4% |
| Q2 2024 | 247 | — | 24.41% | — | $3.21B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying AXSM stock.
Based on Q1 2026 13F filings, institutional ownership of Axsome Therapeutics, Inc. stands at 46.9%, held across 400 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of AXSM, with approximately 3,912,844 shares worth $0.66B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of AXSM, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, Point72 Asset Management, L.P., CITADEL ADVISORS LLC.
Our composite Smart Money Score for AXSM is 52 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
75 institutions opened new positions in AXSM during Q1 2026, while 64 fully exited. 96 added to existing positions and 227 trimmed.
AXSM institutional ownership fell by 3.30 percentage points quarter-over-quarter, with a net change of +11 holders.
The top 10 institutions account for 44.1% of all reported 13F value in AXSM, and the top 25 account for 66.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Axsome Therapeutics, Inc. (AXSM) Institutional Ownership