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PBYI logoPuma Biotechnology, Inc. (PBYI) Earnings History

Annual and quarterly earnings data from 2007 to 2025

TTM Net Income
$24M
Profitable
TTM EPS
$0.48
Diluted
YoY EPS Growth
-1.6%
Slow
Net Margin
13.6%
Profitability
Operating Margin16.3%
Gross Margin74.5%
ROE28.0%
ROA14.5%
Highest Annual Net Income$31M (2025)
Highest Quarterly EPS$0.41 (Q3 2024)
Consecutive Profitable Years4 years
Q1 2026
Net Income-$4M
EPS$-0.07
QoQ Growth-128.4%Declining

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PBYI EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
-1.6%
Slow
3-Year
+210.9%
Excellent
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

PBYI Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202574.5%16.3%13.6%
202472.1%13.4%13.1%
202373.4%13.9%9.2%
202275.8%10.4%0.0%
202174.8%0.5%-11.5%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Puma Biotechnology, Inc. (PBYI) Earnings Overview

As of May 8, 2026, Puma Biotechnology, Inc. (PBYI) reported trailing twelve-month net income of $24M, reflecting -1.6% year-over-year growth. The company earned $0.48 per diluted share over the past four quarters, with a net profit margin of 13.6%.

Looking at the long-term picture, PBYI's historical earnings data spans multiple years. The company achieved its highest annual net income of $31M in fiscal 2025, representing a new all-time high.

Puma Biotechnology, Inc. maintains positive profitability with a gross margin of 74.5%, operating margin of 16.3%, and net margin of 13.6%. The company continues to generate positive earnings from operations. View revenue history →

Compared to peers including RCUS (-$369M net income, -142.9% margin), TGTX ($462M net income, 72.6% margin), PTCT (-$187M net income, 39.4% margin), PBYI has outperformed on profitability metrics. Compare PBYI vs RCUS →

PBYI Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
PBYI logoPBYICurrent
$24M$0.4813.6%28.0%-1.6%—
RCUS logoRCUS
-$369M$-2.94-142.9%-63.3%-4.8%
TGTX logoTGTX
$462M$2.8972.6%102.8%+1746.7%
PTCT logoPTCT
-$187M$-2.2639.4%-+264.5%
ACAD logoACAD
$376M$2.1836.5%39.9%+68.4%
EXEL logoEXEL
$833M$3.1233.7%35.5%+58.0%
Best in group
Lowest in group

PBYI Historical Earnings Data (2007–2025)

19 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025$31M+2.8%$37M$0.6113.6%16.3%
2024$30M+40.2%$31M$0.6213.1%13.4%
2023$22M+1079450.0%$33M$0.459.2%13.9%
2022$2,000+100.0%$24M$0.020.0%10.4%
2021-$29M+51.5%$1M$-0.72-11.5%0.5%
2020-$60M+20.6%-$30M$-1.52-26.7%-13.5%
2019-$76M+33.5%-$76M$-2.13-27.8%-27.8%
2018-$114M+61.1%-$95M$-2.99-45.3%-37.7%
2017-$292M-5.8%-$292M$-7.86-1054.2%-1055.6%
2016-$276M-15.3%-$277M$-8.29--

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Compare PBYI vs DBVT

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PBYI — Frequently Asked Questions

Quick answers to the most common questions about buying PBYI stock.

Is PBYI growing earnings?

PBYI EPS of $0.48 reflects slowing growth at -1.6%, below the 5-year CAGR of N/A. TTM net income is $24M. Expansion rate has moderated.

What are PBYI's profit margins?

Puma Biotechnology, Inc. net margin is +13.6%, with operating margin at +16.3%. Margins sit within typical range for the sector.

How consistent are PBYI's earnings?

PBYI earnings data spans 2007-2025. The current earnings trend is -1.6% YoY. Historical data enables comparison across business cycles.

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PBYI Earnings Over Time (2014–2025)

Net income and EPS trends