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Puma Biotechnology, Inc. (PBYI) Price Target Analysis

Wall Street analyst price targets, ratings consensus & upside potential

Current Price
$5.70
Market reference
Price Target
—
— Upside
Target Range
— — —
Analyst Rating
Buy
19 analysts
Forward P/E22.8x
Trailing P/E9.3x
Forward PEG—
Implied Growth-58.5%
Median Target—
Analyst Spread—

Price Forecast (1 Year)

Last 12 months price action with 12-month analyst target path

Current$5.70
Consensus—
High—
Low—
Model$6.10
Bear Case
$—
—
Consensus
$—
—
Bull Case
$—
—
Valuation Model TargetsConfidence: 32/100
Bear$1228
Base$6
Bull$-36

Analyst Ratings Distribution

Breakdown of 19 published analyst recommendations for PBYI

37% hold / mixed conviction
+11
BearishBullish
Weighted analyst sentiment score based on 19 ratings
ConsensusBuy
Coverage19 Analysts
Net Score+11
Bull / Bear42% / 21%
Strong Buy00%
Buy842%
Hold737%
Sell421%
Strong Sell00%
Strong Buy
00%
Buy
842%
Hold
737%
Sell
421%
Strong Sell
00%
Recommendation Mix42% Buy · 37% Hold · 21% Sell
Buy (8)Hold (7)Sell (4)

PBYI Price Target Analysis

Updated March 1, 2026

As of March 1, 2026, Puma Biotechnology, Inc. (PBYI) has a Wall Street consensus price target of N/A, based on estimates from 19 covering analysts. The company has a market capitalization of $287M.

Analyst price targets range from a low of N/A to a high of N/A.

The current analyst consensus rating is Buy, with 8 analysts rating the stock as a Buy or Strong Buy,7 rating it Hold, and 4 rating it Sell or Strong Sell. The mixed ratings reflect uncertainty about near-term direction.

From a valuation perspective, PBYI trades at a trailing P/E of 9.3x and forward P/E of 22.8x. Analysts expect EPS to grow -58.5% over the next year.

Our proprietary valuation model, which blends historical multiples with forward estimates, suggests a base-case price target of $6.10, with bear and bull scenarios of $1227.73 and $-36.17 respectively. Model confidence stands at 32/100, suggesting limited visibility into future performance.

Investment Context: Price targets represent analyst expectations for the next 12 months and should be considered alongside your own research. Targets are based on analysts' assumptions about earnings growth, margins, and market conditions which may change. For sector-specific context, view other Healthcare stocks.

Analyst Sentiment Comparison

Industry Peer Analysis
Avg Peer Upside+11.7%
Avg Forward P/E16.6x
Peers with Coverage10 / 10
CompanyMarket CapPriceTargetUpsideRatingFwd P/EAnalysts
RVMDRevolution Medicines, Inc.$20.1B$102.02$122.25+19.8%Buy—20
INCYIncyte Corporation$20.1B$101.27$108.90+7.5%Buy13.4x44
GMABGenmab A/S$18.1B$29.44$40.50+37.6%Buy23.2x17
EXELExelixis, Inc.$11.8B$44.06$44.40+0.8%Buy13.3x32
IBRXImmunityBio, Inc.$9.6B$9.78$11.00+12.5%Buy—5
MRUSMerus N.V.$6.8B$90.00$97.00+7.8%Hold—22
CELCCelcuity Inc.$4.8B$111.71$99.33-11.1%Buy—9
CGONCG Oncology, Inc. Common stock$4.6B$58.80$79.00+34.4%Buy—9
ERASErasca, Inc.$3.9B$13.66$9.60-29.7%Buy—9
IDYAIDEAYA Biosciences, Inc.$2.8B$32.20$44.25+37.4%Buy—24

Upside Potential Comparison

GMAB
+37.6%
IDYA
+37.4%
CGON
+34.4%
RVMD
+19.8%
IBRX
+12.5%
MRUS
+7.8%
INCY
+7.5%
EXEL
+0.8%

See PBYI's True Return

Price is only half the story. See total return with reinvested dividends.

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Is PBYI Undervalued?

See our Bear / Base / Bull DCF models and intrinsic value estimates.

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Compare PBYI vs AGIO

See how PBYI stacks up against sector leader Agios Pharmaceuticals, Inc..

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Frequently Asked Questions

What is the PBYI stock price target for 2026?

The consensus price target for PBYI is $N/A, close to the current price of $5.7 (N/A% implied move). Based on 19 analyst estimates, the stock appears fairly valued near current levels.

Is PBYI a buy, sell, or hold?

PBYI has a consensus rating of "Buy" based on 19 Wall Street analysts. The rating breakdown is mixed, with 7 Hold ratings making up the largest segment. The consensus 12-month price target of $N/A implies N/A% upside from current levels.

Is PBYI stock overvalued or undervalued?

PBYI trades at a forward P/E of 22.8x, representing a moderate valuation. With analysts targeting $N/A (N/A% implied move), the stock appears close to fair value.

How high can PBYI stock go?

The most bullish Wall Street analyst has a price target of $N/A for PBYI, while the most conservative target is $N/A. The consensus of $N/A represents the median expectation. Our quantitative valuation model projects a bull case target of $-36 based on optimistic growth and margin assumptions. These targets typically reflect 12-month expectations.

How many analysts cover PBYI stock?

PBYI is well covered by analysts, with 19 analysts providing price targets and ratings. Of these, 0 have Strong Buy ratings, 8 have Buy ratings, 7 recommend Hold, and 4 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.

What is the PBYI stock forecast?

The 12-month PBYI stock forecast based on 19 Wall Street analysts shows a consensus price target of $N/A, with estimates ranging from $N/A (bear case) to $N/A (bull case). The median consensus rating is "Buy". Our proprietary valuation model produces a base case fair value of $6, with bear/bull scenarios of $1228/$-36.

What is PBYI's fair value based on fundamentals?

Our quantitative valuation model calculates PBYI's fair value at $6 (base case), with a bear case of $1228 and bull case of $-36. The model uses discounted cash flow analysis, historical growth rates, and margin mean-reversion to project FY+2 earnings, then applies an appropriate P/E multiple. The model confidence score is 32/100.

What is PBYI's forward P/E ratio?

PBYI trades at a forward P/E ratio of 22.8x based on next-twelve-months earnings estimates compared to a trailing P/E of 9.3x. The higher forward P/E suggests near-term earnings pressure. A forward P/E is useful for comparing valuations when earnings are expected to change significantly.

Should I buy PBYI stock?

PBYI appears fairly valued according to analysts, with a "Buy" rating and minimal upside to the $N/A target. Consider your investment thesis and risk tolerance. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.

Why do PBYI price targets vary so much?

PBYI analyst price targets range from $N/A to $N/A, a NaN% tight range reflecting strong analyst consensus. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $N/A consensus represents the middle ground. Our model's $1228-$-36 range provides an independent fundamental perspective.

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