Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in XNCR held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 13.0M | $157.2M | +9.3% | 17.775% | 0.00% |
| 2 | PRIMECAP MANAGEMENT CO/CA/ | 10.3M | $124.7M | +1.2% | 14.096% | 0.10% |
| 3 | BVF INC/IL | 7.1M | $86.0M | 0.0% | 9.727% | 2.74% |
| 4 | RTW INVESTMENTS, LP | 6.8M | $81.7M | 0.0% | 9.241% | 0.81% |
| 5 | RA CAPITAL MANAGEMENT, L.P. | 4.9M | $59.1M | — | 6.678% | 0.63% |
| 6 | STATE STREET CORP | 4.4M | $52.5M | -3.4% | 5.934% | 0.00% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT LLC | 3.5M | $42.2M | — | 4.773% | 0.00% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 3.1M | $37.4M | — | 4.229% | 0.00% |
| 9 | TCG Crossover Management, LLC | 2.5M | $29.6M | 0.0% | 3.344% | 0.85% |
| 10 | EcoR1 Capital, LLC | 2.2M | $26.3M | -34.2% | 2.977% | 1.12% |
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 1.8M | $21.9M | +3.6% | 2.476% | 0.00% |
| 12 | MORGAN STANLEY | 1.6M | $18.8M | +3.3% | 2.125% | 0.00% |
| 13 | DIMENSIONAL FUND ADVISORS LP | 1.3M | $15.6M | +3.6% | 1.766% | 0.00% |
| 14 | BAKER BROS. ADVISORS LP | 1.1M | $13.3M | 0.0% | 1.503% | 0.08% |
| 15 | UBS Group AG | 1.1M | $13.1M | +69.7% | 1.476% | 0.00% |
| 16 | Legal & General Group Plc | 1.1M | $12.9M | -18.4% | 1.455% | 0.00% |
| 17 | TWO SIGMA INVESTMENTS, LP | 805K | $9.7M | +199.7% | 1.098% | 0.01% |
| 18 | GOLDMAN SACHS GROUP INC | 764K | $9.2M | +1.4% | 1.042% | 0.00% |
| 19 | JOHNSON & JOHNSON | 748K | $9.0M | 0.0% | 1.020% | 1.38% |
| 20 | NORTHERN TRUST CORP | 745K | $9.0M | +10.4% | 1.015% | 0.00% |
| 21 | Jefferies Financial Group Inc. | 720K | $8.7M | 0.0% | 0.982% | 0.06% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 697K | $8.4M | -0.5% | 0.950% | 0.00% |
| 23 | PANAGORA ASSET MANAGEMENT INC | 621K | $7.5M | +6.3% | 0.846% | 0.03% |
| 24 | MILLENNIUM MANAGEMENT LLC | 610K | $7.4M | +2.6% | 0.831% | 0.00% |
| 25 | Lynx1 Capital Management LP | 536K | $6.5M | -24.0% | 0.731% | 1.02% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in XNCR — a direct measure of their conviction.
Filings activity in XNCR during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 201 | 1.5% | 109.22% | 24.96 pp | $988M | 19% |
| Q4 2025 | 204 | +0.5% | 134.18% | +32.02 pp | $1.21B | +31% |
| Q3 2025 | 203 | +5.7% | 102.16% | +35.33 pp | $924M | +53% |
| Q2 2025 | 192 | 4.5% | 66.83% | 18.86 pp | $604M | 22% |
| Q1 2025 | 201 | +3.6% | 85.69% | 89.37 pp | $775M | 51% |
| Q4 2024 | 194 | 7.2% | 175.06% | +29.15 pp | $1.58B | +20% |
| Q3 2024 | 209 | +4.0% | 145.91% | +24.69 pp | $1.32B | +20% |
| Q2 2024 | 201 | — | 121.22% | — | $1.10B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying XNCR stock.
Based on Q1 2026 13F filings, institutional ownership of Xencor, Inc. stands at 109.2%, held across 201 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of XNCR, with approximately 13,035,918 shares worth $0.16B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of XNCR, including TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for XNCR is 40 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
27 institutions opened new positions in XNCR during Q1 2026, while 30 fully exited. 26 added to existing positions and 146 trimmed.
XNCR institutional ownership fell by 24.96 percentage points quarter-over-quarter, with a net change of -3 holders.
The top 10 institutions account for 70.5% of all reported 13F value in XNCR, and the top 25 account for 87.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Xencor, Inc. (XNCR) Institutional Ownership