Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in MDGL held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 2.1M | $1.15B | +0.1% | 9.295% | 5.77% |
| 2 | RTW INVESTMENTS, LP | 2.0M | $1.07B | 0.0% | 8.647% | 9.14% |
| 3 | Jupiter Topco LLC | 1.9M | $1.04B | β | 8.397% | 0.42% |
| 4 | Avoro Capital Advisors LLC | 1.8M | $984.4M | +0.8% | 7.952% | 8.84% |
| 5 | PAULSON & CO. INC. | 1.3M | $719.5M | -3.8% | 5.812% | 27.94% |
| 6 | BlackRock, Inc. | 1.2M | $644.8M | -23.0% | 5.208% | 0.01% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 836K | $448.7M | +1.0% | 3.625% | 0.01% |
| 8 | WELLINGTON MANAGEMENT GROUP LLP | 826K | $443.4M | +18.8% | 3.581% | 0.08% |
| 9 | VANGUARD PORTFOLIO MANAGEMENT LLC | 782K | $419.8M | -7.1% | 3.391% | 0.02% |
| 10 | CITADEL ADVISORS LLC | 688K | $369.5M | +14.2% | 2.985% | 0.02% |
| 11 | STATE STREET CORP | 527K | $283.0M | -13.5% | 2.286% | 0.00% |
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 447K | $240.0M | +85.7% | 1.938% | 0.02% |
| 13 | UBS Group AG | 402K | $215.7M | +241.1% | 1.742% | 0.03% |
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 375K | $201.3M | -17.8% | 1.626% | 0.01% |
| 15 | FMR LLC | 356K | $191.3M | -30.4% | 1.545% | 0.01% |
| 16 | JANE STREET GROUP, LLC | 355K | $190.5M | +48.3% | 1.539% | 0.02% |
| 17 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 324K | $174.0M | -4.8% | 1.406% | 0.52% |
| 18 | Invesco Ltd. | 301K | $161.9M | -8.5% | 1.307% | 0.01% |
| 19 | ARMISTICE CAPITAL, LLC | 288K | $154.6M | +8.8% | 1.249% | 1.89% |
| 20 | GOLDMAN SACHS GROUP INC | 246K | $132.2M | -11.2% | 1.068% | 0.01% |
| 21 | Polar Capital Holdings Plc | 244K | $131.2M | -15.6% | 1.060% | 0.31% |
| 22 | AMERIPRISE FINANCIAL INC | 231K | $124.1M | +135.5% | 1.003% | 0.03% |
| 23 | NORGES BANK | 214K | $114.8M | β | 0.928% | 0.01% |
| 24 | Artisan Partners Limited Partnership | 210K | $112.9M | +14.5% | 0.912% | 0.18% |
| 25 | Pictet Asset Management Holding SA | 193K | $103.5M | +3.0% | 0.837% | 0.10% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in MDGL β a direct measure of their conviction.
Filings activity in MDGL during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 417 | +9.7% | 107.24% | 0.31 pp | $12.93B | +2.4% |
| Q1 2026 | 380 | 2.6% | 107.55% | +0.43 pp | $12.63B | 8.8% |
| Q4 2025 | 390 | +12% | 107.12% | 0.88 pp | $13.84B | +26% |
| Q3 2025 | 347 | +15% | 108.00% | 0.89 pp | $10.97B | +55% |
| Q2 2025 | 302 | 3.5% | 108.89% | 1.53 pp | $7.06B | 9.5% |
| Q1 2025 | 313 | +13% | 110.42% | +0.15 pp | $7.80B | +5.3% |
| Q4 2024 | 276 | +11% | 110.27% | +3.41 pp | $7.41B | +58% |
| Q3 2024 | 248 | β | 106.86% | β | $4.69B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying MDGL stock.
Based on Q2 2026 13F filings, institutional ownership of Madrigal Pharmaceuticals, Inc. stands at 107.2%, held across 417 reporting institutions.
BAKER BROS. ADVISORS LP is the largest reported institutional holder of MDGL, with approximately 2,143,131 shares worth $1.15B as of Q2 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of MDGL, including CITADEL ADVISORS LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, JANE STREET GROUP, LLC.
Our composite Smart Money Score for MDGL is 64 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
72 institutions opened new positions in MDGL during Q2 2026, while 39 fully exited. 205 added to existing positions and 125 trimmed.
MDGL institutional ownership fell by 0.31 percentage points quarter-over-quarter, with a net change of +37 holders.
The top 10 institutions account for 56.4% of all reported 13F value in MDGL, and the top 25 account for 75.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Madrigal Pharmaceuticals, Inc. (MDGL) Institutional Ownership