Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in RARE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 7.3M | $152.9M | +10.1% | 7.425% | 0.00% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 5.4M | $112.8M | — | 5.478% | 0.01% |
| 3 | STATE STREET CORP | 5.0M | $105.2M | +16.7% | 5.107% | 0.00% |
| 4 | AQR CAPITAL MANAGEMENT LLC | 4.6M | $95.9M | +236.5% | 4.656% | 0.04% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 4.2M | $87.8M | — | 4.261% | 0.00% |
| 6 | RTW INVESTMENTS, LP | 3.6M | $76.4M | +21.6% | 3.711% | 0.76% |
| 7 | Sofinnova Investments, Inc. | 3.5M | $73.2M | +4096.7% | 3.556% | 3.84% |
| 8 | SANDS CAPITAL MANAGEMENT, LLC | 3.2M | $67.3M | -7.8% | 3.270% | 0.26% |
| 9 | WELLINGTON MANAGEMENT GROUP LLP | 2.6M | $55.3M | +7.3% | 2.686% | 0.01% |
| 10 | Bellevue Group AG | 2.4M | $49.9M | +92148.1% | 2.421% | 1.19% |
| 11 | CITADEL ADVISORS LLC | 2.4M | $49.7M | -10.9% | 2.412% | 0.02% |
| 12 | Assenagon Asset Management S.A. | 2.3M | $47.3M | +1030.4% | 2.296% | 0.08% |
| 13 | TWO SIGMA INVESTMENTS, LP | 2.2M | $46.2M | +420.2% | 2.244% | 0.04% |
| 14 | FRONTIER CAPITAL MANAGEMENT CO LLC | 2.2M | $45.9M | +11.5% | 2.229% | 0.47% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 1.8M | $38.8M | +0.6% | 1.881% | 0.00% |
| 16 | MILLENNIUM MANAGEMENT LLC | 1.8M | $37.1M | +101.2% | 1.802% | 0.02% |
| 17 | MORGAN STANLEY | 1.5M | $31.4M | -17.8% | 1.526% | 0.00% |
| 18 | JACOBS LEVY EQUITY MANAGEMENT, INC | 1.4M | $30.0M | -18.2% | 1.456% | 0.13% |
| 19 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1.4M | $29.9M | +121.8% | 1.451% | 0.12% |
| 20 | D. E. Shaw & Co., Inc. | 1.3M | $26.4M | +265.8% | 1.283% | 0.02% |
| 21 | Rock Springs Capital Management LP | 1.2M | $25.5M | -3.8% | 1.240% | 1.50% |
| 22 | Jones Hill Capital LP | 1.2M | $24.4M | — | 1.185% | 5.23% |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.1M | $23.8M | -11.3% | 1.155% | 0.00% |
| 24 | Candriam Luxembourg S.C.A. | 1.1M | $23.0M | +37.1% | 1.115% | 0.12% |
| 25 | BANK OF AMERICA CORP /DE/ | 1.0M | $21.9M | -13.8% | 1.065% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in RARE — a direct measure of their conviction.
Filings activity in RARE during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new RARE position in Q1 2026
Institutions that fully closed their RARE position in Q1 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 286 | +2.1% | 83.34% | 4.24 pp | $2.00B | 4.8% |
| Q4 2025 | 280 | 3.4% | 87.58% | 27.25 pp | $2.10B | 24% |
| Q3 2025 | 290 | 3.0% | 114.83% | 22.92 pp | $2.75B | 17% |
| Q2 2025 | 299 | +1.7% | 137.75% | +12.72 pp | $3.30B | +10% |
| Q1 2025 | 294 | 3.6% | 125.03% | 20.46 pp | $2.99B | 14% |
| Q4 2024 | 305 | +4.5% | 145.49% | 43.41 pp | $3.48B | 23% |
| Q3 2024 | 292 | +8.6% | 188.90% | +45.16 pp | $4.52B | +31% |
| Q2 2024 | 269 | — | 143.74% | — | $3.44B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying RARE stock.
Based on Q1 2026 13F filings, institutional ownership of Ultragenyx Pharmaceutical Inc. stands at 83.3%, held across 286 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of RARE, with approximately 7,299,598 shares worth $0.15B as of Q1 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of RARE, including CITADEL ADVISORS LLC, TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for RARE is 52 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
65 institutions opened new positions in RARE during Q1 2026, while 59 fully exited. 98 added to existing positions and 122 trimmed.
RARE institutional ownership fell by 4.24 percentage points quarter-over-quarter, with a net change of +6 holders.
The top 10 institutions account for 44.0% of all reported 13F value in RARE, and the top 25 account for 69.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Ultragenyx Pharmaceutical Inc. (RARE) Institutional Ownership